DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC3 and Dkk2

DIOPT Version :9

Sequence 1:	NP_524928.2	Gene:	NimC3 / 48772	FlyBaseID:	FBgn0001967	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_006501881.1	Gene:	Dkk2 / 56811	MGIID:	1890663	Length:	272	Species:	Mus musculus

Alignment Length:	151	Identity:	35/151 - (23%)
Similarity:	50/151 - (33%)	Gaps:	61/151 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 VCCPGYRTILFGFCEPVCQEA----CPAHSYCAEPDRCHCQRGYEPSHH--------------HT 126
            :||||.| ...|.|.||.:..    .||.......||.|   |:..:|.              |.
Mouse   128 MCCPGTR-CNNGICIPVTESILTPHIPALDGTRHRDRNH---GHYSNHDLGWQNLGRPHSKMPHI 188

  Fly   127 TGHQ----------------------LICRPVCQGG--CPEHSHCVAH-----NECECWPG---- 158
            .||:                      .||:||...|  |.:.....:|     ..|:|..|
Mouse   189 KGHEGDPCLRSSDCIDGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCK 253

  Fly   159 -FKDASSWFSLSLR---CERV 175
             :|||:  :|...|   |:::
Mouse   254 VWKDAT--YSSKARLHVCQKI 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC3	NP_524928.2	MSC	85..>212	CDD:286487	31/146 (21%)
Dkk2	XP_006501881.1	Dickkopf_N	91..141	CDD:368068	6/13 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900