Protein Alignment Hsp70Bc and F44E5.4

DIOPT Version :10

• Sequence 1: NP_650209.1
• Gene: Hsp70Bc / 48583
• FlyBaseID: FBgn0013279
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_496509.1
• Gene: F44E5.4 / 174805
• WormBaseID: WBGene00009691
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 647
• Identity: 445/647 - (68%)
• Similarity: 532/647 - (82%)
• Gaps: 15/647 - (2%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            ||||||||||||||:||:|||||:||.:||:||||||||||:|||:||.||:|.|.||.||||||
 Worm     6 AIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDA 70

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::|:..:..|.|||||.|....|||.|.||.|||.::|.|||||:|||.|||||||.||
 Worm    71 KRLIGRRFDESTVQSDCKHWPFGVKGKQGKPVIEVEVKGEKRQFNPEEISAMVLQKMKETAETYL 135

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |.::.|||||||||||||||||||||..|||||.:|||||||||||||||||.::.|:|||||||
 Worm   136 GHTVKDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGIQDEKNVLIFDL 200

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||:|.|||:|||:||||||||||||||.|::.|...|||||..||:..||||:||||
 Worm   201 GGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDQRMLQHFMNEFKRKTGKDISPNPRAIRRLR 265

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||:||.:|:|:||||.|..||::|||||||||||||.||:||||||.|||:||.
 Worm   266 TACERAKRTLSSSSEACVEVDSLFEGIDLCTKITRARFEELCADLFRKTLEPVEKALRDAKLDKS 330

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            :|.::||||||||:||:|.||::||:||.||.|||||||||:|||||||:|||.:...|:|||||
 Worm   331 KIDEVVLVGGSTRVPKIQKLLKDFFNGKELNCSINPDEAVAFGAAVQAAVLSGVKDETIKDVLLV 395

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            |||||||||||||||||.||:||.|||.|..|||:||:||||||||||||||||||:||:.||||
 Worm   396 DVAPLSLGIETAGGVMTNLIDRNTRIPTKACKTFTTYADNQPGVSIQVYEGERAMTRDNHRLGTF 460

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|||||||||||||||||||:||||||||||::.||||:..|||:|:||||:|::|||||:||::
 Worm   461 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGKSNRITIQNEKGRLTQSDIDRMVHEAKQ 525

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEKE 587
            :..||.:.|:|:.:||.||:|.|.:||::::. :.||...|.:...:..:||:||||||:.|||:
 Worm   526 FEKEDGEQRERVQARNQLEAYAFQIKQALDEY-SSKLSTEDASRAKEAVDETLRWLDSNSLAEKD 589

  Fly   588 EFDHKMEELTRHCSPIMTKMHQQG-----AGAAGGPGANCGQQAGGF--GGY-SGPTVEEVD 641
            |.:.|.:||...|..|:|||||.|     ||.||.||      ..||  ..| .||||||||
 Worm   590 EIEAKDKELKSVCQSILTKMHQSGQSSASAGCAGNPG------TAGFNPNNYPQGPTVEEVD 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bc	NP_650209.1	PTZ00009	2..641	CDD:240227	443/645 (69%)
F44E5.4	NP_496509.1	PTZ00009	1..645	CDD:240227	443/645 (69%)