Protein Alignment Hsp70Aa and hspa4l

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_690505.2
• Gene: hspa4l / 562019
• ZFINID: ZDB-GENE-030131-2412
• Length: 826
• Species: Danio rerio
• Alignment Length: 693
• Identity: 199/693 - (28%)
• Similarity: 346/693 - (49%)
• Gaps: 103/693 - (14%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|||:|.....:.|.:.|.:|.|||:..:|.||:.::.....|.||:.||:|:..|.:|||.
Zfish     1 MSVVGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVH 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVS-DGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            ..|:..||.:|||.:..:....|:.:.. |.|...|.|.|..|.|.|..|::::|:|||:|||:|
Zfish    66 GFKKFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSE 130

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN-----LKGE 189
            ..|.:.:.|.||:||::|.|.:|::..||..|||||.||:||:.||.|||||:.|.     .:..
Zfish   131 HALKKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKP 195

  Fly   190 RNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSN 254
            |||:..|:|..::.|:|.:.::|.| ::.:||.|.:|||.:||..||.:..::||.::|.:::.|
Zfish   196 RNVVFVDIGHSSYQVAIASFNKGKL-KMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDN 259

  Fly   255 PRALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKA 318
            ||||.||....|:.|:.:| :|::..:.|:......|.:.|::|.:|||:|:.|......|:...
Zfish   260 PRALLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSV 324

  Fly   319 LNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQS 383
            :..:|:.:.:|:.|.:|||:||:|.::..:..|| ||:.:.::|.|||||.|:|:|.||||  .:
Zfish   325 MEQSKLSRDEIYAIEVVGGATRMPAIKERISKFF-GKDTSTTLNADEAVARGSALQCAILS--PA 386

  Fly   384 GKIQDVLLVDVAPLSLGI-------ETAGGVMTKLIERNCRIPCK-QTKTFS---TYADNQPGVS 437
            .|:::..:.|..|..:.:       |:.|         .|.:..| ....||   |:...:|...
Zfish   387 FKVREFSITDTVPFPITLRWKSPTDESVG---------ECEVYSKNHPAPFSKIITFHKKEPFDL 442

  Fly   438 IQVYEGERAMTKDNNALGTFDLSGIPPAPRG-VPQIEVTFDLDANGILNVSAK---EMSTGKAKN 498
            ...|.....:...:..:|.|.:..:.|.|.| ..:::|...::.:||.:||:.   |...|:.::
Zfish   443 EAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASLIEKQKGEPED 507

  Fly   499 I------TIKN--------------------------------------DKGRLSQ--------- 510
            :      |::|                                      |:|..|.
Zfish   508 VQMDTEPTVQNEGRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASSSKAKSKVKSV 572

  Fly   511 ---------AEIDR-----MVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDE 561
                     .::||     .|...:|...:|:..::|..::|.:|.||::::..:.......:.|
Zfish   573 DLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKLCGIYEKYVTE 637

  Fly   562 ADKNSVLDKCNDTIRWL-DSNTTAEKEEFDHKLEELTRHCSPI 603
            .:.|.:.....||..|| :.....:||.:.|||.||.::..||
Zfish   638 DESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	198/692 (29%)
hspa4l	XP_690505.2	ASKHA_ATPase-like	2..384	CDD:483947	142/383 (37%)