Protein Alignment Hsp70Aa and Hsc70-1

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_524063.1
• Gene: Hsc70-1 / 39542
• FlyBaseID: FBgn0001216
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 465/643 - (72%)
• Similarity: 542/643 - (84%)
• Gaps: 6/643 - (0%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            :||:|||||||||||||:||||||||||||||||||||||||:|||||||.|||||||||.||:|
  Fly     4 LPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTESERLIGDAAKNQVAMNPNNTIF 68

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ||||||||::||..:..|||||||:|.::.|||:|.||||||.|.|.|||:||||||||:|||||
  Fly    69 DAKRLIGRRFDDATVQSDMKHWPFEVFAENGKPRIRVEYKGERKSFYPEEVSSMVLTKMRETAEA 133

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            |||.::||||:||||||||||||||||||.|||||||||||||||||:||||||....|||||||
  Fly   134 YLGGTVTDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKQGTSERNVLIF 198

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260
            ||||||||||:|||::| :|||::|||||||||||||||||.|...||:||:||||..|.|||||
  Fly   199 DLGGGTFDVSVLTIEDG-IFEVKATAGDTHLGGEDFDNRLVNHFVQEFQRKHKKDLGQNKRALRR 262

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325
            ||||.|||||||||||:|:||||:||||.||||.|:|||||||..||||.|::||.|||.|||||
  Fly   263 LRTACERAKRTLSSSTQASIEIDSLFEGVDFYTSVTRARFEELNGDLFRGTMEPVAKALRDAKMD 327

  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390
            ||||||||||||||||||||.||||||:||.||.|||||||||||||||||||.||:|..:||:|
  Fly   328 KGQIHDIVLVGGSTRIPKVQRLLQDFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEAVQDLL 392

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALG 455
            |:||.||||||||||||||.||:||..||.|||:.|:|||||||||.|||:|||||||:|||:||
  Fly   393 LLDVTPLSLGIETAGGVMTTLIKRNTTIPTKQTQIFTTYADNQPGVLIQVFEGERAMTRDNNSLG 457

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            .|:||.||||||||||:|||||:||||||||:|.|.||||...|||.|||||||:.:|:||||:|
  Fly   458 KFELSAIPPAPRGVPQVEVTFDIDANGILNVTALEKSTGKENRITITNDKGRLSKEDIERMVNDA 522

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTA 584
            |.|...||:.|.||.::|.||||.|.::..: ::..:.:...||:.::..:.::||.|||:|..|
  Fly   523 EAYRQADEQQRDRINAKNQLESYCFQLRSTLDDEHLSSRFSPADRETIQQRSSETIAWLDANQLA 587

  Fly   585 EKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            |::||:||.:||.|.||||:|:::|   |||...|....|...|..|| ||||:||||
  Fly   588 ERQEFEHKQQELERICSPIITRLYQ---GAGMAPPPTAGGSNPGATGG-SGPTIEEVD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	463/640 (72%)
Hsc70-1	NP_524063.1	PTZ00009	1..641	CDD:240227	463/641 (72%)