Protein Alignment Hsp70Aa and Hspa14

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001004257.1
• Gene: Hspa14 / 307133
• RGDID: 1303296
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 512
• Identity: 182/512 - (35%)
• Similarity: 292/512 - (57%)
• Gaps: 16/512 - (3%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |.|||:.||.|.:||.||:.|:.:::|||.|:|.||:.||:::.|:::|..||.....|..:||.
  Rat     1 MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAVVAYSEREQVVGLAAKQSRIRNISSTVV 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ..|:::||...||:..:.:......|:...||.:..::...|:|..:||:::.::.:||||||.:
  Rat    66 KVKQILGRSTADPQAQKYISESKCLVIEKNGKLQYEIDTGEETKLVSPEDVARLIFSKMKETAHS 130

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNL-KGERNVLI 194
            .||....|.|:|||..|.:.|:.|..:|...||.||||:|:||:||.||||:.::. .|:.|||:
  Rat   131 VLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDCPTGKSNVLV 195

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALR 259
            |.|||.:..:||:.::.| ::.|.||....::||..|.:.|..:||.||:|.:|.|:|.:.||:.
  Rat   196 FKLGGTSLSLSIMEVNSG-MYRVLSTNTSDNIGGVHFTDSLAQYLASEFQRLFKHDVRGSARAMM 259

  Fly   260 RLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKM 324
            :|..:||.||.:||:...|...:|:|:|||||...|||||||.||:.||...::.|...|..:..
  Rat   260 KLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAVRALLQQSGF 324

  Fly   325 DKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDV 389
            ....|:.:||.|||:|||::|.|::|.|...:|..||.|||.:..|||::|.||.|.:|....|.
  Rat   325 TADDINKVVLCGGSSRIPRLQQLIKDLFPAGDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDS 389

  Fly   390 LLVDVAP---LSLGIETAG-GVMTKLIERNCRIPCKQTKTFSTYADNQPG----VSIQVYEGE-R 445
            :|::.:.   |..|::.:| ...|.|......:|.::..|...     ||    |.:::||.| :
  Rat   390 VLIECSARDILVKGVDESGANRFTVLFPSGTPLPARRQHTLQA-----PGSISSVCLELYESEGK 449

  Fly   446 AMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIK 502
            ...|:........|..:.....|:..|.....:..:|.|.|:..:..|||.:.||::
  Rat   450 NSVKEETKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQETGKCEAITVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	181/511 (35%)
Hspa14	NP_001004257.1	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	150/376 (40%)