Protein Alignment Hsp70Aa and lsh1

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_592867.1
• Gene: lsh1 / 2541537
• PomBaseID: SPAC1F5.06
• Length: 848
• Species: Schizosaccharomyces pombe
• Alignment Length: 690
• Identity: 172/690 - (24%)
• Similarity: 306/690 - (44%)
• Gaps: 124/690 - (17%)

  Fly     4 IGIDLGTTYSCVGVYQHG-KVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :.||.||.::...:.:.| .:||:......|...|.|||..:||:.|..|.|.....|.:::.:.
pombe    25 LAIDYGTEWTKAALIKPGIPLEIVLTKDTRRKEQSAVAFKGNERIFGVDASNLATRFPAHSIRNV 89

  Fly    68 KRLIG---------RKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYK-GESKRFAPEEISSMVLT 122
            |.|:.         :||        ...:|...:.:..:...|:.:. .:.:.::.|||.:|.:.
pombe    90 KELLDTAGLESVLVQKY--------QSSYPAIQLVENEETTSGISFVISDEENYSLEEIIAMTME 146

  Fly   123 KMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLK 187
            .....||....|.|||.|:|||.:||:.||....:|..|...:||.:|::..|.|:.|.|.::..
pombe   147 HYISLAEEMAHEKITDLVLTVPPHFNELQRSILLEAARILNKHVLALIDDNVAVAIEYSLSRSFS 211

  Fly   188 GERNV-LIFDLGGGTFDVSILTID--EGS-------LFEVRSTA-GDT-HLGGEDFDNRLVTHLA 240
            .:... :|:|.|.|:...::::.|  |||       :..:|:.| |.| .|.|.:.:.:|:..:.
pombe   212 TDPTYNIIYDSGSGSTSATVISFDTVEGSSLGKKQNITRIRALASGFTLKLSGNEINRKLIGFMK 276

  Fly   241 DEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCA 305
            :.|.:|:..||..|.|||.||...|.|.|..||:::||...|:.|.:|.||..|::|:..|.||.
pombe   277 NSFYQKHGIDLSHNHRALARLEKEALRVKHILSANSEAIASIEELADGIDFRLKITRSVLESLCK 341

  Fly   306 DLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYG 370
            |:....::|:.|||..|.:...:|:.|:|.||::|||.:||.|.|:.....::.::|.|||...|
pombe   342 DMEDAAVEPINKALKKANLTFSEINSIILFGGASRIPFIQSTLADYVSSDKISKNVNADEASVKG 406

  Fly   371 AAVQAAILSGDQSGKIQDVLLVDVAP----LSLG------------------------IETAG-- 405
            ||...|.|:  :|.:::.:::.|:..    ||||                        :.|.|
pombe   407 AAFYGASLT--KSFRVKPLIVQDIINYPYLLSLGTSEYIVALPDSTPYGMQHNVTIHNVSTIGKH 469

  Fly   406 ------------GVMTKL----IERNCRIPCKQTK-TFSTYADNQPGVSIQVYEGERAMTKDNNA 453
                        |..|..    :|:.|....|..: :||  :|...|:.:.:   ...||.::..
pombe   470 PSFPLSNNGELIGEFTLSNITDVEKVCACSNKNIQISFS--SDRTKGILVPL---SAIMTCEHGE 529

  Fly   454 L--------------GTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGK-AKNITIKN 503
            |              |:.|.||:    |......:.|.....|.::.:|..:::.| .:.:.|..
pombe   530 LSSKHKLGDRVKSLFGSHDESGL----RNNESYPIGFTYKKYGEMSDNALRLASAKLERRLQIDK 590

  Fly   504 DKGRLSQA--EIDRMVNEAEKYADEDE------KHRQRITSRNALESYVFNVKQAVEQAPAGKLD 560
            .|.....|  |::.::..|:...|:||      ....:|...:::|||.:.::.. .|:|..::.
pombe   591 SKAAHDNALNELETLLYRAQAMVDDDEFLEFANPEETKILKNDSVESYDWLIEYG-SQSPTSEVT 654

  Fly   561 EADKNSVLDKCNDTIRWLDSNTTAEK------EEFDHKLE 594
            :..|     |.:||::.:.......|      |.|.:.||
pombe   655 DRYK-----KLDDTLKSISFRFDQAKQFNTSLENFKNALE 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	172/690 (25%)
lsh1	NP_592867.1	ASKHA_NBD_HSP70_HYOU1	23..412	CDD:466828	118/394 (30%)