Protein Alignment Hsp70Aa and hsp-3

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001370435.1
• Gene: hsp-3 / 180880
• WormBaseID: WBGene00002007
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 366/622 - (58%)
• Similarity: 481/622 - (77%)
• Gaps: 11/622 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT--DSERLIGDPAKNQVAMNPRNTVFD 66
            |||||||||||||||::|:|||||||||||.|||||||:  ..:|||||.||||:.:||.||:||
 Worm    36 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFD 100

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||.|:|..:..|:|||||||:....||.:.|:...::|:|.|||:|:|||.||||.||:|
 Worm   101 AKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESY 165

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:.:.:||:||||||||:|||||||||.||||||:||||||||||:||||||. .||||:|:||
 Worm   166 LGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 229

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||:||||.| :|||.:|.|||||||||||.|::.:....:|:|..||||.:.||:::|
 Worm   230 LGGGTFDVSMLTIDNG-VFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKL 293

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |...|:|||.||:..:..:||::||:|:||...::||:||||..||||.||:||:|.|.|:.:.|
 Worm   294 RREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKK 358

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            ..:|:||||||||||||||.|:::||:||..:..||||||||||||||..::||::.  ..:::|
 Worm   359 DDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEED--TGEIVL 421

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||::||||.||||||||.||..||.|:::.|||.|||||.|:|||:||||.|||||:.||.
 Worm   422 LDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGK 486

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |||:|:||||||||||||||::|.||||:|:|::..||....|||.||:.|||..:|:||:|:||
 Worm   487 FDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAE 551

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAVE--QAPAGKLDEADKNSVLDKCNDTIRWLDSNTTA 584
            |:|::|:|.:.:..:||.||||.:|:|..:|  :...|||||.||.::.:...:.|.||.||..|
 Worm   552 KFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEA 616

  Fly   585 EKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGA 621
            ..||...:.::|.....||::|:::.   |||||..|
 Worm   617 SAEELKEQKKDLESKVQPIVSKLYKD---AGAGGEEA 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	366/622 (59%)
hsp-3	NP_001370435.1	PTZ00009	32..648	CDD:240227	364/618 (59%)