Protein Alignment Hsp70Aa and hsp-1

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_503068.1
• Gene: hsp-1 / 178507
• WormBaseID: WBGene00002005
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 479/642 - (74%)
• Similarity: 546/642 - (85%)
• Gaps: 9/642 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |:|||||||||||||:.||||||||||||||||||||||||:||||||.|||||||||.||||||
 Worm     6 AVGIDLGTTYSCVGVFMHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTVFDA 70

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVS-DGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||:|||.:..|||||||||:| :|.|||:.||||||:|.|.|||||||||.||||||||:
 Worm    71 KRLIGRKFDDPAVQSDMKHWPFKVISAEGAKPKVQVEYKGENKIFTPEEISSMVLLKMKETAEAF 135

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||.::.|||:||||||||||||||||||.|||||||||||||||||:||||||...|||||||||
 Worm   136 LGTTVKDAVVTVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGHGERNVLIFD 200

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.|...|||||:||||.|||||||||
 Worm   201 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFCAEFKRKHKKDLASNPRALRRL 264

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.||||||||||::|:||||:||||.||||.::|||||||||||||:|:.||||:|.||||||
 Worm   265 RTACERAKRTLSSSSQASIEIDSLFEGIDFYTNITRARFEELCADLFRSTMDPVEKSLRDAKMDK 329

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .|:||||||||||||||||.||.|.|.||.||.||||||||||||||||||||||:|..:||:||
 Worm   330 SQVHDIVLVGGSTRIPKVQKLLSDLFSGKELNKSINPDEAVAYGAAVQAAILSGDKSEAVQDLLL 394

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :|||||||||||||||||.||:||..||.|..:||:||:||||||.|||||||||||||||.||.
 Worm   395 LDVAPLSLGIETAGGVMTALIKRNTTIPTKTAQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 459

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|||||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||||||
 Worm   460 FELSGIPPAPRGVPQIEVTFDIDANGILNVSATDKSTGKQNKITITNDKGRLSKDDIERMVNEAE 524

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAVE-QAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            ||..:||..:.||.::|.||||.||:||.:| :....|:...||..:.|||::.::|||||.|||
 Worm   525 KYKADDEAQKDRIGAKNGLESYAFNLKQTIEDEKLKDKISPEDKKKIEDKCDEILKWLDSNQTAE 589

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            ||||:|:.::|....:||::|::|   .||...|||..|..|||.|   |||:||||
 Worm   590 KEEFEHQQKDLEGLANPIISKLYQ---SAGGAPPGAAPGGAAGGAG---GPTIEEVD 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	477/640 (75%)
hsp-1	NP_503068.1	PTZ00009	1..614	CDD:240227	462/611 (76%)