Protein Alignment Hsp70Aa and hspa8

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_002937574.2
• Gene: hspa8 / 100496320
• XenbaseID: XB-GENE-955426
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 645
• Identity: 480/645 - (74%)
• Similarity: 550/645 - (85%)
• Gaps: 7/645 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:|||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.|||||
 Frog     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||:::|..:..|||||||.|:||.|:||:.||||.|:|.|.|||||||||.||||.||||
 Frog    70 AKRLIGRRFEDAVVQSDMKHWPFNVISDSGRPKVQVEYKAETKSFYPEEISSMVLVKMKEIAEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:::|:|||||||||||||||||||||.|:|||||||||||||||:||||||.:..||||||||
 Frog   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.|...|||||:|||:..|.||:|||
 Frog   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFVAEFKRKHKKDIIDNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:|:||.||||.::|||||||.|||||.||.||||||.|||:||
 Frog   264 RTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .||||||||||||||||:|.||||||:||.||.||||||||||||||||||||||:|..:||:||
 Frog   329 SQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||||||||||||||.||:||..||.|||:||:||:||||||.|||||||||||||||.||.
 Frog   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||.|||
 Frog   459 FELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAE 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAVE-QAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            ||..||||.|.:::|:|:||||.||:|..|| :...||:.:.||..:|||||:.|.|||.|.|||
 Frog   524 KYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLKGKISDEDKQKILDKCNEVISWLDKNQTAE 588

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGF---GGYSGPTVEEVD 642
            ||||:|:.:||.:.|:||:||::|...|...|.||...|  |||.   |..||||:||||
 Frog   589 KEEFEHQQKELEKVCNPIITKLYQSAGGMPGGMPGGFPG--AGGAPSGGASSGPTIEEVD 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	478/643 (74%)
hspa8	XP_002937574.2	PTZ00009	1..613	CDD:240227	462/608 (76%)