Protein Alignment Hsp70Aa and hspa5

DIOPT Version :10

• Sequence 1: NP_731651.1
• Gene: Hsp70Aa / 48581
• FlyBaseID: FBgn0013275
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_002941690.1
• Gene: hspa5 / 100492570
• XenbaseID: XB-GENE-480060
• Length: 655
• Species: Xenopus tropicalis
• Alignment Length: 619
• Identity: 375/619 - (60%)
• Similarity: 483/619 - (78%)
• Gaps: 10/619 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            :|||||||||||||:::|:|||||||||||.|||||||| :.||||||.||||:..||.||||||
 Frog    33 VGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDA 97

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||.::||.:.:|:|:.||||:....||.|.|:...:.|.|||||||:|||.||||||||||
 Frog    98 KRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYL 162

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |:.:|.||:||||||||:|||||||||.||||||:||||||||||:||||||. :||:|:|:|||
 Frog   163 GKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKK-EGEKNILVFDL 226

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:||||.| :|||.:|.|||||||||||.|::.|....:|:|..||:|.:.||:::||
 Frog   227 GGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLR 290

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ...|:|||.|||..::.|||::.|||:||...::||:||||..||||:|::||:|.|:||.:.|.
 Frog   291 REVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKS 355

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            .|.:||||||||||||:|.|:::||:||..:..|||||||||||||||.:|||||.  ..|::|:
 Frog   356 DIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQD--TGDLVLL 418

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||.||:|||||.||||||||.||..:|.|:::.|||.:||||.|:|:||||||.:||||:.||||
 Frog   419 DVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTF 483

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:||||||||||||||||::|.||||.|:|::..||....|||.||:.||:..||:|||.:|||
 Frog   484 DLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEK 548

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQAV--EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            :|:||:|.::||.:||.||||.:::|..:  ::...|||...||.::.....:.|.||:|:..::
 Frog   549 FAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSD 613

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGP 619
            .|||..|.:||.....||:.|::   .||||..|
 Frog   614 IEEFKAKKKELEEIVQPIVGKLY---GGAGAPPP 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Aa	NP_731651.1	PTZ00009	2..642	CDD:240227	375/619 (61%)
hspa5	XP_002941690.1	HSP70	32..636	CDD:394970	370/606 (61%)