Protein Alignment heph and ptbp1b

DIOPT Version :10

• Sequence 1: NP_001247399.1
• Gene: heph / 48571
• FlyBaseID: FBgn0011224
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_001116126.1
• Gene: ptbp1b / 321220
• ZFINID: ZDB-GENE-030131-9796
• Length: 564
• Species: Danio rerio
• Alignment Length: 634
• Identity: 300/634 - (47%)
• Similarity: 388/634 - (61%)
• Gaps: 110/634 - (17%)

  Fly   299 TSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAA----VMAPASDNNNQDLATKKAKLEPGTVL 359
            |.|:........:|..:...:...||||||.|...    :|:.|::.|:    :||.|
Zfish     7 TELYPMGSSYAELDVVHDIAVGTKRGSDELFSCVTSGPYIMSSAANGND----SKKFK------- 60

  Fly   360 AGGI---AKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVS 421
             |.|   |..|:|||:|.:||:..||:|||||:|||:|||:|:||||||||:||..|.:|.:||:
Zfish    61 -GDIRSPAVPSRVIHVRKLPNDINEAEVIALGLPFGKVTNLLMLKGKNQAFLEMNSEEAAQTMVT 124

  Fly   422 CYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANS 486
            .|:...|.:|...:::|:|||:|||||...|...|.:
Zfish   125 YYSSVTPVIRNHPIFMQYSNHKELKTDNSPNQVRAQA---------------------------- 161

  Fly   487 SSDSNSAMGILQNTSAVNAG----GNTNAAG--GPNTVLRVIVESLMYPVSLDILHQIFQRYGKV 545
                     .||..:||..|    |..:.:|  ||:.|||||||:|.|||:||:|||||.::|.|
Zfish   162 ---------ALQAVNAVQTGSLTLGGVDPSGMTGPSPVLRVIVENLFYPVTLDVLHQIFSKFGTV 217

  Fly   546 LKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDF 610
            ||::||||||.||||:|:.|..:|||||..|||||||||||||||..||||:||||||||||||:
Zfish   218 LKVITFTKNNQFQALLQFTDGLTAQHAKLALDGQNIYNGCCTLRISFSKLTSLNVKYNNDKSRDY 282

  Fly   611 TNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGL----GAPGVL------------ 659
            |.|.||.|:                        .:|:|..:.:    .|||::
Zfish   283 TRPDLPTGD------------------------SQPALEHHAVAAAFAAPGIISAAPYASAHAFP 323

  Fly   660 PPFAL---GLGTPLTGGYNNALPNLA--AFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPD 719
            |.||:   ||..|   |...||.:|.  ..:.|.:.|.:...|.:.|...|:||||||.|.|||.
Zfish   324 PAFAIQQAGLTIP---GVPGALASLTIPGAAAAAAAASRLGFPTLTGTHCVMLVSNLNPERVTPH 385

  Fly   720 ALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLP 784
            .||.||||||||.||||::|||::|||||::..||.||||||:..:|:|:|:|:..|||..||:|
Zfish   386 CLFILFGVYGDVLRVKIMFNKKENALIQMSDGTQAQLAMSHLNGQKLYGRPLRITLSKHTTVQMP 450

  Fly   785 KEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVK 849
            :||..|.|||:|||.:|||||||||||||.||:|||:||||||||.|..|||:|..|.|:...||
Zfish   451 REGHEDQGLTKDYSNSPLHRFKKPGSKNYSNIFPPSSTLHLSNIPPSVVEDDLKLLFGSSGALVK 515

  Fly   850 AFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI 898
            .||||.|||||||:|:.|||||:.:||:.|||.|.|::|||||||||.|
Zfish   516 NFKFFQKDRKMALIQMSSVEEAIESLIQFHNHDLGENHHLRVSFSKSTI 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
heph	NP_001247399.1	hnRNP-L_PTB	366..898	CDD:273733	280/558 (50%)
ptbp1b	NP_001116126.1	hnRNP-L_PTB	69..564	CDD:273733	280/558 (50%)