Protein Alignment Pp1-13C and PPP6C

DIOPT Version :10

• Sequence 1: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001116827.1
• Gene: PPP6C / 5537
• HGNCID: 9323
• Length: 342
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 122/268 - (45%)
• Similarity: 170/268 - (63%)
• Gaps: 15/268 - (5%)

  Fly    36 LCLKSREILLAQPILLELEAPLKICGDIHGQYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLE 100
            ||....::||.:..:..:..|:.:|||||||:|||..||..||..|:.||:|:||:||||..|||
Human    64 LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLE 128

  Fly   101 TICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRY-TIKLWKTFTDCFNCLPVVAIVD 164
            |...|||.|.|:.:...|||||||...|.::|||||||:.:| ....|:..|..|:.|.|.|::|
Human   129 TFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALID 193

  Fly   165 EKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDP-DKDTIGWGENDRGVSFTFGAE 228
            |:|.|.|||||||:.:::|||.|.|..::|.:|..|||:|||| |.||  |..:.||..:.|||:
Human   194 EQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDT--WAISPRGAGWLFGAK 256

  Fly   229 VVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQI 293
            |..:|:..::|.|||||||:|.:||:|....:|||::||||||....|..::|           :
Human   257 VTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIM-----------V 310

  Fly   294 LKPVEKRK 301
            .|.|..|:
Human   311 FKDVNTRE 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	119/261 (46%)
PPP6C	NP_001116827.1	MPP_PP2A_PP4_PP6	5..326	CDD:277360	122/268 (46%)