Protein Alignment Pp1-13C and PPP4C

DIOPT Version :10

• Sequence 1: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_002711.1
• Gene: PPP4C / 5531
• HGNCID: 9319
• Length: 307
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 139/303 - (45%)
• Similarity: 201/303 - (66%)
• Gaps: 12/303 - (3%)

  Fly     1 MAEVLNLESIISRLLEVRGARPGKNVQLSEGEIRGLCLKSREILLAQPILLELEAPLKICGDIHG 65
            |||:.:|:..|.:|....        .:.|.|::.||.|:||||:.:..:..:::|:.:||||||
Human     1 MAEISDLDRQIEQLRRCE--------LIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHG 57

  Fly    66 QYYDLLRLFEYGGYPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINR 130
            |:|||..||..||..||.||||:||:||||..|:||..||||.|::|.:...|:|||||...|.:
Human    58 QFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ 122

  Fly   131 IYGFYDECKRRY-TIKLWKTFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVP 194
            :|||||||.|:| ::.:|:..|:.|:.|.:.||:|.||||.||||||.:.:::|||.|.|..:||
Human   123 VYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVP 187

  Fly   195 DQGLLCDLLWSDPDKDTIGWGENDRGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKR 259
            ..|.:||||||||: ||.|||.:.||..:.||::||.:|...:|:|:||||||:|.:||::....
Human   188 HDGPMCDLLWSDPE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251

  Fly   260 QLVTLFSAPNYCGEFDNAGAMMSVDNTLMCSFQILK--PVEKR 300
            .::|::||||||....|..|::.:|..|...|.|.:  |.|.|
Human   252 TVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	133/292 (46%)
PPP4C	NP_002711.1	MPP_PP2A_PP4_PP6	6..290	CDD:277360	133/292 (46%)