Protein Alignment Pp1-13C and PPEF1

DIOPT Version :10

• Sequence 1: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_006231.2
• Gene: PPEF1 / 5475
• HGNCID: 9243
• Length: 653
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 98/332 - (29%)
• Similarity: 153/332 - (46%)
• Gaps: 81/332 - (24%)

  Fly    39 KSREILLAQPILLELE-APLK---ICGDIHGQYYDLLRLFEYGGYPPEAN-YLFLGDYVDRGKQS 98
            :::::|...|....:: :|.|   ||||:||:..||..:|...|.|.|.| |:|.||:|||||.|
Human   145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNS 209

  Fly    99 LETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTI---KLWKTFTDCFNCLPVV 160
            :|.:.:|....:.|..:..|.|||||...:|..|||..|...:|.:   ::.:...:.:..||:.
Human   210 IEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIG 274

  Fly   161 AIVDEKIFCCHGGLS--PDLTSMEQIRR------IMRPTDV------------------------ 193
            .|||.:|...|||:|  .||..:.::.|      ::.||:.
Human   275 TIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIK 339

  Fly   194 ----PDQGL-------LCDLLWSDPDKDTIGWGEND------RGVSFTFGAEVVVKFLQKHDLDL 241
                |.:.|       :.|:|||||.      |:|.      ||....||.:|..|.|.|:.|.:
Human   340 TNGSPTEHLTEHEWEQIIDILWSDPR------GKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKM 398

  Fly   242 ICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDNTLMCS--------FQILK--- 295
            :.|:|:...:|||.....::||:|||.||..|..|.||.:.     :||        :|:.|
Human   399 LIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIK-----LCSGTTPRFFQYQVTKATC 458

  Fly   296 --PVEKR 300
              |:.:|
Human   459 FQPLRQR 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	96/326 (29%)
PPEF1	NP_006231.2	MPP_RdgC	115..452	CDD:277364	94/317 (30%)
		Catalytic	121..455		95/320 (30%)
		FRQ1	487..635	CDD:444056
		EF-hand_7	568..636	CDD:463900
		IQ	18..37	CDD:197470