Protein Alignment Pp1-13C and Ppp3cc

DIOPT Version :10

• Sequence 1: NP_524921.1
• Gene: Pp1-13C / 48531
• FlyBaseID: FBgn0003132
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001291920.1
• Gene: Ppp3cc / 19057
• MGIID: 107162
• Length: 522
• Species: Mus musculus
• Alignment Length: 294
• Identity: 114/294 - (38%)
• Similarity: 172/294 - (58%)
• Gaps: 30/294 - (10%)

  Fly    24 KNVQLSEGEI-RGLCLK----SREILLAQPILLELEAPLKICGDIHGQYYDLLRLFEYGGYPPEA 83
            ||..:.||.: ..:.||    ...||..:..::|:|||:.:|||:|||::||::|||.||.|...
Mouse    43 KNHLVKEGRVEEEVALKIINDGAAILKQEKTMIEVEAPITVCGDVHGQFFDLMKLFEVGGSPSNT 107

  Fly    84 NYLFLGDYVDRGKQSLETICLLLAYKIKYSENFFLLRGNHECASINRIYGFYDECKRRYTIKLWK 148
            .|||||||||||..|:|.:..|.:.||.:.:..|||||||||..:...:.|..||:.:|:..::.
Mouse   108 RYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTEYFTFKQECRIKYSEMVYD 172

  Fly   149 TFTDCFNCLPVVAIVDEKIFCCHGGLSPDLTSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTIG 213
            .....|:|||:.|:::::..|.|||:||::|.:|.||::.|.::.|..|.:||||||||.:|
Mouse   173 ACMHTFDCLPLAALLNQQFLCVHGGMSPEITCLEDIRKLDRFSEPPAFGPVCDLLWSDPLED--- 234

  Fly   214 WGEND----------RGVSFTFGAEVVVKFLQKHDLDLICRAHQVVEDGYEFFAKRQ------LV 262
            :|...          ||.|:.|....|.:|||.:.|..|.|||:..:.||..:.|.|      |:
Mouse   235 YGSEKTLEHYTHNTVRGCSYFFSYPAVCEFLQNNSLLSIIRAHEAQDAGYRMYRKNQATGFPSLI 299

  Fly   263 TLFSAPNYCGEFDNAGAMMSVDNTLM------CS 290
            |:||||||...::|..|::..:|.:|      ||
Mouse   300 TIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp1-13C	NP_524921.1	MPP_PP1_PPKL	6..296	CDD:277359	114/294 (39%)
Ppp3cc	NP_001291920.1	MPP_PP2B	37..341	CDD:277361	114/294 (39%)
		Catalytic. /evidence=ECO:0000305	52..343		110/285 (39%)
		SAPNY motif. /evidence=ECO:0000250|UniProtKB:Q08209	303..307		3/3 (100%)
		Calcineurin B binding. /evidence=ECO:0000250|UniProtKB:P16298	344..366
		Calmodulin-binding. /evidence=ECO:0000250|UniProtKB:P16298	394..408
		Autoinhibitory segment. /evidence=ECO:0000250|UniProtKB:P16298	409..416
		Autoinhibitory domain. /evidence=ECO:0000250|UniProtKB:P16298	467..489
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..522