Protein Alignment alphaTry and ACR

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 94/283 - (33%)
• Similarity: 134/283 - (47%)
• Gaps: 32/283 - (11%)

  Fly     4 IVILLSAVVCALGGTV--PEGLL----PQLDGRIVGGSATTISSFPWQISLQ-----RSGSHSCG 57
            :::|..:||.....|.  |.||.    ||...|||||.|....::||.:|||     ....|:||
Human    10 LLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCG 74

  Fly    58 GSIYSANIIVTAAHCL---QSVSASVLQVRAGS-TYWSSGGVVAK-----VSSFKNHEGYNANTM 113
            ||:.::..::|||||.   .:|....|...|.. ||.::..|.|.     |.....||.||:.|.
Human    75 GSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATE 139

  Fly   114 VNDIAVIRLSSSLSFSSSIKAISLATYN---PANGASAAVSGWGTQSSGSSSIPSQLQYVNVNIV 175
            .||||::.::..:|....|....|..:.   |....|..|:|||.....:....|.|....|:::
Human   140 GNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLI 204

  Fly   176 SQSQCASSTYGYGSQIRNTMICAA-ASGK-DACQGDSGGPLV------SGGVLVGVVSWGYGCAY 232
            ....| :||..|..:::.|.:||. ..|| |.|||||||||:      |..|:||:.|||.|||.
Human   205 DLDLC-NSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCAR 268

  Fly   233 SNYPGVYADVAVLRSWVVSTANS 255
            :..||:|.......:|:.|...|
Human   269 AKRPGIYTATWPYLNWIASKIGS 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	82/243 (34%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	82/243 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421