Protein Alignment alphaTry and PRSS33

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_690851.2
• Gene: PRSS33 / 260429
• HGNCID: 30405
• Length: 280
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 92/279 - (32%)
• Similarity: 132/279 - (47%)
• Gaps: 42/279 - (15%)

  Fly     2 LKIVILLSAVVCALGGTVPEGL------LPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSI 60
            |::::||     .||....:|.      .|::..|||||.......:|||.|:|..|:|.||||:
Human     7 LQVLLLL-----VLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSL 66

  Fly    61 YSANIIVTAAHCL--QSVSAS----VLQVRAGSTYWSSGGVVAKVSSFKNHEGYNANTMVNDIAV 119
            .:...::|||||.  :::.|.    :..:|.|||  |...:...|........|:.:....|:|:
Human    67 IAPQWVLTAAHCFPRRALPAEYRVRLGALRLGST--SPRTLSVPVRRVLLPPDYSEDGARGDLAL 129

  Fly   120 IRLSSSLSFSSSIKAISLAT--YNPANGASAAVSGWGTQSSGSSSIP----SQLQYVNVNIVSQS 178
            ::|...:..|:.::.:.|..  ..|..|....|:|||:...|   :|    ..||.|.|.::...
Human   130 LQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPG---VPLPEWRPLQGVRVPLLDSR 191

  Fly   179 QCASSTYGYGSQIRNT-------MICAA--ASGKDACQGDSGGPLV---SGG-VLVGVVSWGYGC 230
            .| ...|..|:.:...       .:||.  ...||||||||||||.   ||. |||||||||.||
Human   192 TC-DGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGC 255

  Fly   231 AYSNYPGVYADVAVLRSWV 249
            |..|.||||..||....|:
Human   256 ALPNRPGVYTSVATYSPWI 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	84/243 (35%)
PRSS33	NP_690851.2	Tryp_SPc	37..275	CDD:238113	84/244 (34%)