Protein Alignment alphaTry and Cfd

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 258
• Identity: 79/258 - (30%)
• Similarity: 128/258 - (49%)
• Gaps: 21/258 - (8%)

  Fly     5 VILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTA 69
            :::|.|.|||          .|..|||:||......:.|:..|:|.:|:|.|||::.....:::|
Mouse    10 LVILGAAVCA----------AQPRGRILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSA 64

  Fly    70 AHCLQSVS-ASVLQVRAGSTYWSSGGVVAK---VSSFKNHEGYNANTMVNDIAVIRLSSSLSFSS 130
            |||:..|: ...:||..|:...|:.....:   |.|...|.|...:::.:|:.:.:||.:.|...
Mouse    65 AHCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGP 129

  Fly   131 SIKAISLATYNPAN---GASAAVSGWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIR 192
            .::.:.| .|....   |....|:|||..:..... |..|..:.|:|::::.|...||..|....
Mouse   130 HVRPLPL-QYEDKEVEPGTLCDVAGWGVVTHAGRR-PDVLHQLRVSIMNRTTCNLRTYHDGVVTI 192

  Fly   193 NTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWVVSTAN 254
            | |:||.::.:|.|:||||.|||.|..:.|||:||.. |.....||||..|:..|.|:.:..|
Mouse   193 N-MMCAESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITN 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	70/226 (31%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	70/228 (31%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)