Protein Alignment alphaTry and KLK8

DIOPT Version :10

• Sequence 1: NP_476771.1
• Gene: alphaTry / 48316
• FlyBaseID: FBgn0003863
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 78/230 - (33%)
• Similarity: 115/230 - (50%)
• Gaps: 15/230 - (6%)

  Fly    28 DGRIVGGSATTISSFPWQISLQRSGSHSCGGSIYSANIIVTAAHCLQSVSASVLQVRAGS-TYWS 91
            :.:::||......|.|||.:|.:.....|||.:...|.::|||||    ......||.|. :..:
Human    75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSLQN 135

  Fly    92 SGGVVAKVSSFKN--HEGYNANTMV---NDIAVIRLSSSLSFSSSIKAISLATYNPANGASAAVS 151
            ..|...::...::  |..||::.:.   :|:.:::|....|..|.:|.||||.:....|....||
Human   136 KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVS 200

  Fly   152 GWGTQSSGSSSIPSQLQYVNVNIVSQSQCASSTYGYGSQIRNTMICAAAS-GKDACQGDSGGPLV 215
            ||||.:|...:.|..|....|.|..|.:|..:   |..||.:.|:||.:| |.|.||||||||||
Human   201 GWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA---YPGQITDGMVCAGSSKGADTCQGDSGGPLV 262

  Fly   216 SGGVLVGVVSWGYG-CAYSNYPGVYADVAVLRSWV 249
            ..|.|.|:.|||.. |..|:.||||.::.....|:
Human   263 CDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaTry	NP_476771.1	Tryp_SPc	30..249	CDD:214473	77/226 (34%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	77/226 (34%)