Protein Alignment Aprt and APRT

DIOPT Version :10

• Sequence 1: NP_476637.1
• Gene: Aprt / 48224
• FlyBaseID: FBgn0000109
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_000476.1
• Gene: APRT / 353
• HGNCID: 626
• Length: 180
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 82/178 - (46%)
• Similarity: 116/178 - (65%)
• Gaps: 2/178 - (1%)

  Fly     7 AEDKLDYVKSKIGEYPNFPKEGILFRDIFGALTDPKACVYLRDLLVDHIRES-APEAEVIVGLDS 70
            |:.:|..|:.:|..:|:||..|::||||...|.||.:......||..|::.: ....:.|.||||
Human     2 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDS 66

  Fly    71 RGFLFNLLIATELGLGCAPIRKKGKLAGEVVSVEYKLEYGIDTFELQKSAIKPGQKVVVVDDLLA 135
            |||||...:|.||||||..|||:|||.|..:...|.||||....|:||.|::|||:|||||||||
Human    67 RGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLA 131

  Fly   136 TGGSLVAATELIGKVGGVVVESLVVMELVGLEGRKRL-DGKVHSLIKY 182
            |||::.||.||:|::...|:|.:.::||..|:||::| .....||::|
Human   132 TGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQY 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Aprt	NP_476637.1	PRK02304	9..182	CDD:235028	80/174 (46%)
APRT	NP_000476.1	apt	9..179	CDD:273437	79/169 (47%)