Protein Alignment hbn and crx

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_694419.1
• Gene: crx / 81881
• ZFINID: ZDB-GENE-010403-1
• Length: 281
• Species: Danio rerio
• Alignment Length: 273
• Identity: 91/273 - (33%)
• Similarity: 119/273 - (43%)
• Gaps: 72/273 - (26%)

  Fly   150 PRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKF 214
            |||.||.|||||..||..||..|.||:|||:|.||::|::::|.|:||||||:|||||.|:::
Zfish    35 PRKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ-- 97

  Fly   215 MNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAA--AAAAGLLP 277
              |..:|     |..|..|.....||..|...||:..|....|        .|..  :.:||..|
Zfish    98 --QQTSG-----QPKPRPPKKKSSPPPDLTSDPGTSSSVVAAP--------TPTVPPSVSAGTAP 147

  Fly   278 QHLMAPHYKLPNFHTLLSQYMGLSNL-NGIFGAGAAAAAAAA----SAGYPQNLSLHAGLSAMSQ 337
            ..:.:|              ..||.| :.:.|:|.......|    |.|.|.:.|...|
Zfish   148 VSVWSP--------------TSLSPLPDPLCGSGTPCVQRPAPYPMSYGQPSSYSQGYG------ 192

  Fly   338 VSPPCSNSSPRE-----SPKLVPHPTPPHATPPAGGNGGGGL--LT----GGLISTAAQSPNSAA 391
                   |||..     ||.|.|..|...|:       ||.|  ||    ||.:|   |||:.::
Zfish   193 -------SSPYFSGLDCSPYLSPMTTQLSAS-------GGALSPLTVPSMGGSLS---QSPSLSS 240

  Fly   392 GASSNASTPVSVV 404
            ...|.||...|.|
Zfish   241 QGYSTASLGFSSV 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	34/55 (62%)
crx	NP_694419.1	homeodomain	38..97		35/58 (60%)
		Homeodomain	49..94	CDD:459649	27/44 (61%)
		TF_Otx	152..230	CDD:427350	26/111 (23%)