Protein Alignment hbn and DRGX

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: XP_011538391.1
• Gene: DRGX / 644168
• HGNCID: 21536
• Length: 298
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 83/270 - (30%)
• Similarity: 109/270 - (40%)
• Gaps: 66/270 - (24%)

  Fly   143 DLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQ--------- 198
            |..|....||.||:|||||..||..||..|.:|.||||||||:|||:::|:|||||
Human    23 DFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQLANSCLKTE 87

  Fly   199 --------------------------VWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPL-GI 236
                                      ||||||||||||.|:..:..:.|...|...:...|: .|
Human    88 LQIEINDTIIEHSEVEDHNFSLKGARVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNI 152

  Fly   237 PLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQY---- 297
            ..||   ||.....:.|......:|.:...||.......||..|:    ....:...||..
Human   153 NSPP---PGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLL----NTATYAQALSHVASLK 210

  Fly   298 ------------MGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRES 350
                        ||||.| ..:|..:...|:.|:..........|.|.:.:.:  |.::|||  .
Human   211 GGPLCSCCVPDPMGLSFL-PTYGCQSNRTASVATLRMKAREHSEAVLQSANLL--PSTSSSP--G 270

  Fly   351 PKLVPHPTPP 360
            |  |..|.||
Human   271 P--VAKPAPP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	40/90 (44%)
DRGX	XP_011538391.1	Homeodomain	34..125	CDD:459649	40/90 (44%)
		OAR	236..253	CDD:461067	2/16 (13%)