Protein Alignment hbn and Nobox

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_570939.1
• Gene: Nobox / 18291
• MGIID: 108011
• Length: 527
• Species: Mus musculus
• Alignment Length: 291
• Identity: 70/291 - (24%)
• Similarity: 105/291 - (36%)
• Gaps: 72/291 - (24%)

  Fly   154 RRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQD 218
            :::||.:.:.||.:|||.|::..|||...|.:::..:.::..|:.||||||||||||.||...::
Mouse   137 KKTRTLYRSDQLEELERIFQEDHYPDSDKRHEISQMVGVTPQRIMVWFQNRRAKWRKVEKLNEKE 201

  Fly   219 -KAGYLLP------EQGLPE----FPLGI---PLPPHGL----PGHPGSMQSEFWPPHFALHQHF 265
             |.|...|      .:..||    .|..:   |:||..:    |..|..:.||.....|..::..
Mouse   202 TKNGPAAPSADSSQHRSAPELLDPMPTDLEPGPVPPENILDVFPEPPMLLTSEQTLTPFQNNEGA 266

  Fly   266 NPAAAAAAGLLPQHLMAPHYKLP-----------------------------NFHTLLSQYMGLS 301
            ...|.....|.|..:...:..||                             ::.|.::.....|
Mouse   267 ERVAVTPPLLSPPPIRRANLPLPLGPVQTPQVLPPMRDVPGSDSIYKDKAYVSWGTSIASPPTYS 331

  Fly   302 NLNGIFGAGAAAAAAAASAGYPQ--NLSLHAGLSAMSQVSPPCSNSSPRESPKLVPH-------- 356
            ||..:......|::...|....|  :|.|...|.:.....||.....|...|.|.|.
Mouse   332 NLEDLGSQDYQASSQLGSFQLSQAPHLPLFPSLQSQFPYLPPFPYPIPSSMPFLPPEDSLFSFPF 396

  Fly   357 -----------PTPPHA----TPPAGGNGGG 372
                       |.||..    .|||...|.|
Mouse   397 GFSGDSSQDYCPGPPPGQILLQPPAENMGTG 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	23/55 (42%)
Nobox	NP_570939.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..126
		COG5576	94..213	CDD:227863	30/75 (40%)
		Homeodomain	137..193	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..245		11/50 (22%)
		PHA03247	<206..454	CDD:223021	41/222 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..306		4/34 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	488..527