Protein Alignment hbn and Phox2a

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_032913.1
• Gene: Phox2a / 11859
• MGIID: 106633
• Length: 280
• Species: Mus musculus
• Alignment Length: 286
• Identity: 81/286 - (28%)
• Similarity: 102/286 - (35%)
• Gaps: 133/286 - (46%)

  Fly   145 SDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWR 209
            |.:...||.||.|||||:.||.:|||.|.:|.|||::|||:||:::||:||||||||||||||:|
Mouse    82 SGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146

  Fly   210 KREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAG 274
            |:|:                                                       ||:|.|
Mouse   147 KQER-------------------------------------------------------AASAKG 156

  Fly   275 LLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVS 339
                                                 ||.|..|..| ....|.....|..|..|
Mouse   157 -------------------------------------AAGATGAKKG-EARCSSEDDDSKESTCS 183

  Fly   340 P-PCSNSS-------PRESPKLVPHPTP------PHATPPAG-------GNGGGGLLTG------ 377
            | |.|.:|       ...||:|.|.|.|      |...|..|       |.||||..||
Mouse   184 PTPDSTASLPPPPAPSLASPRLSPSPLPAALGSGPGPQPLKGALWAGVAGGGGGGPGTGAAELLK 248

  Fly   378 -------------GLISTAAQSPNSA 390
                         |::|:..:.|..|
Mouse   249 AWQPAEPGPGPFSGVLSSFHRKPGPA 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	38/55 (69%)
Phox2a	NP_032913.1	Homeodomain	91..147	CDD:459649	38/55 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..244		36/191 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..280		4/15 (27%)