Protein Alignment hbn and Alx4

DIOPT Version :10

• Sequence 1: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_031468.1
• Gene: Alx4 / 11695
• MGIID: 108359
• Length: 399
• Species: Mus musculus
• Alignment Length: 271
• Identity: 85/271 - (31%)
• Similarity: 108/271 - (39%)
• Gaps: 102/271 - (37%)

  Fly   132 DELSSSLNNGHDLSDMERPR-KVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEA 195
            |..|:.:.:..:.:|.|..: |.||:|||||::||.:||:.|:||.||||:.||.||||.||:||
Mouse   180 DRASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEA 244

  Fly   196 RVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFA 260
            |||||||||||||||||:|                                 |.||.
Mouse   245 RVQVWFQNRRAKWRKRERF---------------------------------GQMQQ-------- 268

  Fly   261 LHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQN 325
            :..||:.|                |:|| ..|....|..:.|.:.|...|||:...|...
Mouse   269 VRTHFSTA----------------YELP-LLTRAENYAQIQNPSWIGNNGAASPVPACVV----- 311

  Fly   326 LSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGG----------NGGGGLL----T 376
                           ||..         ||....|||.||..|          :|.|..:    .
Mouse   312 ---------------PCDP---------VPACMSPHAHPPGSGASSVSDFLSVSGAGSHVGQTHM 352

  Fly   377 GGLISTAAQSP 387
            |.|...|..||
Mouse   353 GSLFGAAGISP 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	41/55 (75%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..133
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..206		7/25 (28%)
		Homeodomain	203..259	CDD:459649	41/55 (75%)
		OAR	375..393	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	379..392