Protein Alignment tws and tws

DIOPT Version :10

• Sequence 1: NP_476880.1
• Gene: tws / 47877
• FlyBaseID: FBgn0004889
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_061506495.1
• Gene: tws / 1274649
• VectorBaseID: AGAMI1_012410
• Length: 548
• Species: Anopheles gambiae
• Alignment Length: 535
• Identity: 424/535 - (79%)
• Similarity: 457/535 - (85%)
• Gaps: 38/535 - (7%)

  Fly     1 MGRWGRQ--SPVLEP----------------PDPQMQTTPP---PPTLPPRTFMRQSSITKIGNM 44
            :|||||.  :||..|                ..|....:||   ||.:|||..:||||.||||.|
Mosquito    16 IGRWGRSTTNPVTIPGSTASGTADGYSYTLTSGPSPPHSPPINMPPPIPPRPVIRQSSFTKIGYM 80

  Fly    45 LNTAININGAKKPAS-------------NGEASWCFSQIKGALDDDVTDADIISCVEFNHDGELL 96
            :|||  :||.||..|             |||.||||||||||||||||:||||||||||||||||
Mosquito    81 INTA--VNGTKKQFSSGSSSNSSSSNSGNGETSWCFSQIKGALDDDVTEADIISCVEFNHDGELL 143

  Fly    97 ATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPV 161
            ||||||||||||||||:|||:.|||||||||||||||||||||||||||||||||||||::||..
Mosquito   144 ATGDKGGRVVIFQRDPSSKASTPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLRRKNQS 208

  Fly   162 HFLLSTNDKTVKLWKVSERDKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFA 226
            ||||||||||:||||||||||...||||:|:||.||||.::.:|||||:|.:.|:|||||||.||
Mosquito   209 HFLLSTNDKTIKLWKVSERDKRVEGYNTREDNGSIRDPASINSLRVPSIKPMDLMVEASPRRIFA 273

  Fly   227 NAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTE 291
            ||||||||||||||||||:||||||||||||||:.:||:|||||||.||||||||||||||||||
Mosquito   274 NAHTYHINSISVNSDQETYLSADDLRINLWHLEITDQSFNIVDIKPANMEELTEVITAAEFHPTE 338

  Fly   292 CNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPE--NPTNRSFFSEIISSISDVKLSNSGRYMI 354
            ||||||||||||||||||||:||||||:|.|||||  :.||:|||.|||||||||||||||||||
Mosquito   339 CNVFVYSSSKGTIRLCDMRSSALCDRHAKLFEEPEDVDTTNKSFFREIISSISDVKLSNSGRYMI 403

  Fly   355 SRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFF 419
            |||||||||||||||||||||||||||||.|||||||||||||||||||||.||:||||||||||
Mosquito   404 SRDYLSIKVWDLHMETKPIETYPVHEYLRTKLCSLYENDCIFDKFECCWNGNDSAIMTGSYNNFF 468

  Fly   420 RVFDRNSKKDVTLEASRDIIKPKTVLKPRKVCTGGKRKKDEISVDCLDFNKKILHTAWHPEENII 484
            |:||||:.|||||||||||||||||||||||||||||||||||||||.|||:||||||||.||||
Mosquito   469 RIFDRNTNKDVTLEASRDIIKPKTVLKPRKVCTGGKRKKDEISVDCLAFNKRILHTAWHPLENII 533

  Fly   485 AVAATNNLFIFQDKF 499
            |||||||||||||||
Mosquito   534 AVAATNNLFIFQDKF 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tws	NP_476880.1	CDC55	65..495	CDD:227498	381/431 (88%)
		WD40 repeat	84..132	CDD:293791	44/47 (94%)
		WD40 repeat	150..227	CDD:293791	54/76 (71%)
		WD40 repeat	233..272	CDD:293791	33/38 (87%)
		WD40 repeat	283..323	CDD:293791	36/39 (92%)
		WD40 repeat	341..377	CDD:293791	35/35 (100%)
		WD40 repeat	398..439	CDD:293791	35/40 (88%)
tws	XP_061506495.1	None