Protein Alignment tws and ppp2r2ca

DIOPT Version :10

• Sequence 1: NP_476880.1
• Gene: tws / 47877
• FlyBaseID: FBgn0004889
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001032471.1
• Gene: ppp2r2ca / 100002802
• ZFINID: ZDB-GENE-051120-168
• Length: 452
• Species: Danio rerio
• Alignment Length: 428
• Identity: 307/428 - (71%)
• Similarity: 362/428 - (84%)
• Gaps: 3/428 - (0%)

  Fly    74 LDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANP---RRGEYNVYSTFQSHEP 135
            |.|.||:||:||.||||..|:||||||||||||||||:..||..:.   ..||||||||||||||
Zfish    15 LRDYVTEADVISTVEFNQTGDLLATGDKGGRVVIFQRETESKGESEELGESGEYNVYSTFQSHEP 79

  Fly   136 EFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSERDKSFGGYNTKEENGLIRDPQ 200
            :|||||||||||||||||||.|::..||||||||||:||||||||||...|||.|:|.|.|:|..
Zfish    80 DFDYLKSLEIEEKINKIRWLPQQDAAHFLLSTNDKTIKLWKVSERDKRPEGYNLKDEEGRIKDIS 144

  Fly   201 NVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSY 265
            .||:||||.:|...|:||..|||.|||.||||:||||||||.||:|||||||||:|||::.::|:
Zfish   145 TVTSLRVPVLKPTDLMVEVRPRRVFANGHTYHVNSISVNSDGETYLSADDLRINMWHLDITDRSF 209

  Fly   266 NIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTN 330
            |||||||.|||:||||||||||||..|::|||||||||:||||||.:||||||||.|||||:|.|
Zfish   210 NIVDIKPANMEDLTEVITAAEFHPQHCHLFVYSSSKGTLRLCDMRESALCDRHSKIFEEPEDPGN 274

  Fly   331 RSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCI 395
            ||||||||||:||||.|:||||:::||||::||||||||..|:|||.||||||::||||||||||
Zfish   275 RSFFSEIISSVSDVKFSHSGRYLLTRDYLTVKVWDLHMEKGPVETYQVHEYLRSRLCSLYENDCI 339

  Fly   396 FDKFECCWNGKDSSIMTGSYNNFFRVFDRNSKKDVTLEASRDIIKPKTVLKPRKVCTGGKRKKDE 460
            ||||||.||..||.||||:||:|||:|||.:.:.|||||.|:..||:.||:.|:|.|||:|::.:
Zfish   340 FDKFECVWNSTDSVIMTGAYNSFFRMFDRETGRGVTLEAWRESSKPRAVLRTRRVYTGGRRRRGD 404

  Fly   461 ISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDK 498
            :.||.|||.|||||.||||.|||||:||||||:||||:
Zfish   405 VGVDSLDFTKKILHMAWHPAENIIAIAATNNLYIFQDR 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tws	NP_476880.1	CDC55	65..495	CDD:227498	303/423 (72%)
		WD40 repeat	84..132	CDD:293791	34/50 (68%)
		WD40 repeat	150..227	CDD:293791	49/76 (64%)
		WD40 repeat	233..272	CDD:293791	28/38 (74%)
		WD40 repeat	283..323	CDD:293791	31/39 (79%)
		WD40 repeat	341..377	CDD:293791	24/35 (69%)
		WD40 repeat	398..439	CDD:293791	26/40 (65%)
ppp2r2ca	NP_001032471.1	CDC55	19..439	CDD:227498	301/419 (72%)
		WD40 repeat	25..76	CDD:293791	34/50 (68%)
		WD40 repeat	94..172	CDD:293791	50/77 (65%)
		WD40 repeat	177..213	CDD:293791	25/35 (71%)
		WD40 repeat	227..278	CDD:293791	40/50 (80%)
		WD40 repeat	285..321	CDD:293791	24/35 (69%)
		WD40 repeat	342..393	CDD:293791	30/50 (60%)
		WD40 repeat	416..439	CDD:293791	18/22 (82%)