| Sequence 1: | NP_524896.2 | Gene: | Abd-B / 47763 | FlyBaseID: | FBgn0000015 | Length: | 493 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_082292.1 | Gene: | Nanog / 71950 | MGIID: | 1919200 | Length: | 305 | Species: | Mus musculus |
| Alignment Length: | 168 | Identity: | 49/168 - (29%) |
|---|---|---|---|
| Similarity: | 74/168 - (44%) | Gaps: | 17/168 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 295 GPNYRPDQTTSAAAAAAYMNEAERH---VSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYS 356
Fly 357 SSGASGGLSVGAVGPCTP--NPGLHEWTGQVSVRKK--RKPYSKFQTLELEKEFLFNAYVSKQKR 417
Fly 418 WELARNLQLTERQVKIWFQNRRMKNKKNSQRQANQQNN 455 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Abd-B | NP_524896.2 | Homeodomain | 388..444 | CDD:459649 | 24/57 (42%) |
| Nanog | NP_082292.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | 5/22 (23%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..95 | 14/58 (24%) | |||
| Sufficient for interaction with SALL4. /evidence=ECO:0000269|PubMed:16840789 | 96..155 | 24/58 (41%) | |||
| Homeodomain | 98..153 | CDD:459649 | 22/54 (41%) | ||
| Required for DNA-binding. /evidence=ECO:0000250|UniProtKB:Q9H9S0 | 123..152 | 15/28 (54%) | |||
| PTZ00395 | <190..>250 | CDD:185594 | |||
| 10 X repeats starting with a Trp in each unit | 198..247 | ||||
| Sufficient for transactivation activity | 198..247 | ||||
| Sufficient for strong transactivation activity | 248..305 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||