DRSC/TRiP Functional Genomics Resources

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Protein Alignment repo and CRX

DIOPT Version :10

Sequence 1:NP_477026.1 Gene:repo / 47285 FlyBaseID:FBgn0011701 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_000545.1 Gene:CRX / 1406 HGNCID:2383 Length:299 Species:Homo sapiens


Alignment Length:111 Identity:30/111 - (27%)
Similarity:44/111 - (39%) Gaps:34/111 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 TQAGTVS------TMSDEERQKLLKEIEMFQMIKKKREAMEKENEMLSRRCEELTMSIKCQKHQR 65
            |...|||      |.:.|||....|....    |.|:|...|:..|..|..||:.::|| ..:|:
Human  1576 TMPATVSELAVPTTNNSEERTATPKTAAE----KTKKEEYMKKLHMQERAVEEVKLAIK-PFYQK 1635

  Fly    66 QELMKERI-----------------ELGPENGKLAKDAKIRLKAYI 94
            :|:.||..                 |:.|     .|.|.: :|||:
Human  1636 REVTKEEYKDILRKAVQKICHSKSGEINP-----VKVANL-VKAYV 1675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
repoNP_477026.1 Homeodomain 313..361 CDD:459649
CRXNP_000545.1 Homeodomain 40..93 CDD:459649
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 93..155
TF_Otx 164..249 CDD:427350
Blue background indicates that the domain is not in the aligned region.

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