Protein Alignment Fur1 and RSPO2

DIOPT Version :10

• Sequence 1: NP_001262954.1
• Gene: Fur1 / 47220
• FlyBaseID: FBgn0004509
• Length: 1478
• Species: Drosophila melanogaster
• Sequence 2: NP_848660.3
• Gene: RSPO2 / 340419
• HGNCID: 28583
• Length: 243
• Species: Homo sapiens
• Alignment Length: 145
• Identity: 27/145 - (18%)
• Similarity: 53/145 - (36%)
• Gaps: 38/145 - (26%)

  Fly  1220 NTAACLKWSDRKCLECNDSAYMFEDQCYDVCPVHTYPLDK------------------------- 1259
            |..:|  :|...|.:|....|:...:|:|.||....||::
Human   100 NCDSC--FSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNNRT 162

  Fly  1260 --FQAEEDEQDDEVTRGPVN-----PYSSSPMDHSLLMSNSLDDKQDPLQAEDRRRRSSLTQLVE 1317
              |:...:.:..::.:.||.     |..:......:.|.:....|:.| :|:::|.:....:|:|
Human   163 CGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTP-KAKEKRNKKKKRKLIE 226

  Fly  1318 VPSR---VCAACDRS 1329
            ....   |..|.||:
Human   227 RAQEQHSVFLATDRA 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fur1	NP_001262954.1	S8_pro-domain	234..309	CDD:465126
		Peptidases_S8_Protein_convertases_Kexins_Fur in-lik	332..621	CDD:173789
		P_proprotein	701..787	CDD:460225
		FU	1320..>1350	CDD:214589	4/13 (31%)
RSPO2	NP_848660.3	Furin-like_2	40..141	CDD:464939	12/42 (29%)
		FU	90..134		10/35 (29%)
		TSP1_spondin	145..198	CDD:480609	4/52 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..243		10/39 (26%)