Protein Alignment Fur1 and mbtps1

DIOPT Version :10

• Sequence 1: NP_001262954.1
• Gene: Fur1 / 47220
• FlyBaseID: FBgn0004509
• Length: 1478
• Species: Drosophila melanogaster
• Sequence 2: NP_954683.2
• Gene: mbtps1 / 326710
• ZFINID: ZDB-GENE-030131-4909
• Length: 1074
• Species: Danio rerio
• Alignment Length: 1006
• Identity: 188/1006 - (18%)
• Similarity: 290/1006 - (28%)
• Gaps: 433/1006 - (43%)

  Fly   129 VVFLCNINVGFVAGSVATAASSAGGSSPAAPSSAPSSPPTVAVPPPPPPSSALKVDPNGQSPVLP 193
            :|.|| :.|.|:           |...|...:...|.|.....|||.|.::...:.||.....|.
Zfish     2 IVRLC-LLVAFL-----------GAKLPLVGTEEDSGPFLTPFPPPLPLNADAHLSPNCSQLTLK 54

  Fly   194 PYVLDYETGGKAKLTPNNGKFGQSGSSGSNNNHIVGHYTHTWAVHIPNGDNGMADAVAKDHGFVN 258
               ||:.|                        .:|   .|.:.|..    ||...|.|:. .|::
Zfish    55 ---LDFST------------------------QVV---KHEYIVAF----NGYFTAKARS-DFIS 84

  Fly   259 LGKIFDDHYHFAHHKVSKRSLSPATHHQTRLDDDDRVHWAKQQRAKSRS-----------KRD-- 310
                                        :.|.|.|.|.|...:|....|           |:|
Zfish    85 ----------------------------SALRDVDAVKWRIVRRDNPASDYPSDFEVVEIKQDTR 121

  Fly   311 ----------FI-RMRPSRTSSRAMSMVD-----AMSFNDSKWPQMWY------------LNRGG 347
                      :| |:.|.|...|::...|     |...||::|.|.|.            |:...
Zfish   122 NSLLTLQDHPYIKRVTPQRMVLRSLKFTDSGTDGASPCNDTRWVQKWQSWQSSRPLRRTSLSLSS 186

  Fly   348 GL-----------DMNVIP-----------AWKMGITGKGVVVTILDDGLESDHPDIQD-----N 385
            |.           .:..||           .|:||.||.||.|.:.|.||...||..::     |
Zfish   187 GFWHATGRHSSRRLLRAIPRHVAQILQADVLWQMGHTGSGVKVAVFDTGLSEKHPHFKNVKERTN 251

  Fly   386 YDPKASYDVNSHDDDPMPHYDMTDSNRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGD- 449
            :..:.:.|               |...|||..||.:|:...   |. |.|..:.:...|:...:
Zfish   252 WTNEKTLD---------------DGLGHGTFVAGVIASMRE---CQ-GFAPDSELHIFRVFTNNQ 297

  Fly   450 ------VTDAVEARSLSLNPQHIDIYSASWGPDD--DGKTVDGPGELASRAFIEGTTKGRGGKGS 506
                  ..||.....|    :.||:.:.|.|..|  |...||...||.:...
Zfish   298 VSYTSWFLDAFNYAIL----KKIDVLNLSIGGPDFMDHPFVDKVWELTANKV------------- 345

  Fly   507 IFIWASGNGGREQDNCNCDGYTNSIWTLSISSATEEGHVPWYSEKCSSTL------------ATT 559
            |.:.|.||.|......|  ...:.:..:.:.....|.::..:|.:..:|.            ..|
Zfish   346 IMVSAIGNDGPLYGTLN--NPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIVT 408

  Fly   560 YSSGGQGEKQVVTTDLHHSCTVSHTGTSASAPLAAGIAALVLQSNQNLTWRDL------------ 612
            |.||.:|      :.|...|. |.:|||.::|:.||...|:..:..|   |:|
Zfish   409 YGSGVRG------SGLKEGCR-SLSGTSVASPVVAGAVTLLASTVLN---RELVNPASMKQALIA 463

  Fly   613 ----------------------QHIVVRTAKP-ANL----------------------------- 625
                                  .:.::.:.|| |:|
Zfish   464 SARRLPGVNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTI 528

  Fly   626 ----------------KDPSWS----RNG--VGRRVSHS------FGY---------------GL 647
                            :.|.|.    :||  |...||:|      .||               |:
Zfish   529 VNVTILNGMGVTGRIVEKPIWQPYLPQNGDYVDVAVSYSPVLWPWAGYLAVSISVAKKAASWEGI 593

  Fly   648 MDAAEMVRV---ARNWKAVPEQQRCEINAPHVDKVI--PPRT----------------------- 684
            .....||.|   |.|..|:..:....:..|...|::  |||:
Zfish   594 AQGHVMVTVASPAENDSAIGGEMTSTVKLPVKVKIVPTPPRSKRILWDQYHNLRYPPGYFPRDNL 658

  Fly   685 --------------HITLQLTVNHCRSVNY-LEHVQAKIT-----------------------LT 711
                          |...:....|.||:.| :|.:.|.||                       :|
Zfish   659 RMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPITCFDASQYGTLLMVDSEEEYFPEEIT 723

  Fly   712 SQRR---GDIQLFLRSP-ANTSVTLLTPRIHDNSRSGFNQW----------PFMS--VHTWGESP 760
            ..||   ..:.|.:.|. .||||........:|:|    ||          |.::  :..||.:
Zfish   724 KLRRDIDNGLSLIVFSDWYNTSVMRKVKFYDENTR----QWWMPDTGGANVPALNDLISVWGMA- 783

  Fly   761 QGNWQLEIHNEGRYMGHALLREWSLIFYGTTQSIG--PNDPISVP---KPSGSEATTPNSSSTTS 820
                    .::|.|.|...|.:..: :|.:..||.  |.|.|.:.   |..|.|.....::...:
Zfish   784 --------FSDGLYEGDFTLADHDM-YYASGCSIARFPEDGIVIAQTLKDQGLEVLKQETAVVEN 839

  Fly   821 NLHQAYSPQYPRIPPNNFGSSPS-GGSKLPL 850
                        :|......:|| ||.::.|
Zfish   840 ------------VPVLGLYQTPSDGGGRIAL 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fur1	NP_001262954.1	S8_pro-domain	234..309	CDD:465126	13/85 (15%)
		Peptidases_S8_Protein_convertases_Kexins_Fur in-lik	332..621	CDD:173789	75/382 (20%)
		P_proprotein	701..787	CDD:460225	24/124 (19%)
		FU	1320..>1350	CDD:214589
mbtps1	NP_954683.2	Peptidases_S8_SKI-1_like	218..470	CDD:173805	66/299 (22%)