Protein Alignment Men and NAD-ME2

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_191966.2
• Gene: NAD-ME2 / 828222
• AraportID: AT4G00570
• Length: 607
• Species: Arabidopsis thaliana
• Alignment Length: 572
• Identity: 221/572 - (38%)
• Similarity: 335/572 - (58%)
• Gaps: 39/572 - (6%)

  Fly   222 LLDKRYSKGLAFTHEERQQLGIHGMLP----YVVREPSEQVEHCRALLARLDQD------LDKYM 276
            |.|..::|...|...||.:|||.|:||    ..|::....:|..|:|......:      |.|:.
plant    43 LHDPWFNKDTGFPLTERDRLGIRGLLPPRVMTCVQQCDRFIESFRSLENNTKGEPENVVALAKWR 107

  Fly   277 YLISLSERNERLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLK 341
            .|..|.:|||.|:|.||..:|....|::|||||||.||.||.:::..:||:.|.||||.:..::.
plant   108 MLNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCQNYSGLYRRPRGMYFSAKDKGEMMSMIY 172

  Fly   342 NWPETDVRAIVVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESIL 406
            |||...|..||:|||.|||||||||..|:|||:|||.:|.|.|||.|.:.|||.||||||.|.:|
plant   173 NWPAPQVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRVLPIMLDVGTNNEKLL 237

  Fly   407 EDPLYIGLRERRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFND 471
            ::.||:|:|:.|..|:.|.|.|||||.|...|: ...::|||||....||..|.:||..||.|||
plant   238 QNDLYLGVRQPRLEGEEYLEIIDEFMEAAFTRW-PKAVVQFEDFQAKWAFGTLERYRKKFCMFND 301

  Fly   472 DIQGTASVAVAGLLASLKIKKTQLKD---NTLLFLGAGEAALGIANLCLMAM-KVEGLTEEEAKA 532
            |:||||.||:||||.:::.:...:.|   ..::.:|||.|.||:..:.:.|: ::.|::|.||..
plant   302 DVQGTAGVALAGLLGTVRAQGRPISDFVNQKIVVVGAGSAGLGVTKMAVQAVARMAGISESEATK 366

  Fly   533 RIWMVDSRGVITRDRPKGGLTEHKLHFAQLHEPID-----TLAEAVRKVRPNVLIGAAAQGGAFN 592
            ..:::|..|::|.:|.|  |....:.||:  .|.:     ::.|.|:||||:||:|.:..||.||
plant   367 NFYLIDKDGLVTTERTK--LDPGAVLFAK--NPAEIREGASIVEVVKKVRPHVLLGLSGVGGIFN 427

  Fly   593 QEILELMADINE-TPIIFALSNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKF-YPGQ 655
            :|:|:.|.:.:. .|.|||:||||..|||||.:|:.:..|..:|||||||..|...|.|. :..|
plant   428 EEVLKAMRESDSCKPAIFAMSNPTLNAECTAADAFKHAGGNIVFASGSPFENVELENGKVGHVNQ 492

  Fly   656 GNNSYIFPGVALGVLCAGMLNIPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAER 720
            .||.|:|||:.||.|.:|...:.:.:...|:|.||..::.:::.||.|||.:::|...:..:...
plant   493 ANNMYLFPGIGLGTLLSGARIVTDGMLQAASECLASYMTDEEVQKGILYPSINNIRHITAEVGAA 557

  Fly   721 IVEYAYKNGLA----TVRPEPVNKLA------FIKAQMYDLDYPRSVPATYK 762
            ::..|..:.:|    .|.|:.::.::      :|...|:   :|...|..::
plant   558 VLRAAVTDDIAEGHGDVGPKDLSHMSKEDTVNYITRNMW---FPVYSPLVHE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	220/565 (39%)
NAD-ME2	NP_191966.2	PLN03129	17..604	CDD:215594	221/568 (39%)