Protein Alignment Men and Menl-2

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_001027424.2
• Gene: Menl-2 / 3772692
• FlyBaseID: FBgn0029153
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 234/540 - (43%)
• Similarity: 342/540 - (63%)
• Gaps: 2/540 - (0%)

  Fly   222 LLDKRYSKGLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNE 286
            :::.:|:||||||.:|||:|||.|::|..||...:|:....|.......|:.::.||.::..|:.
  Fly    42 VMNGKYNKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHR 106

  Fly   287 RLFYNVLSSDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAI 351
            ||:|..:..:|...:|:|||||||.....|.|..|.|..:||||.|||||.|::.||.:..|:||
  Fly   107 RLYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEGVKAI 171

  Fly   352 VVTDGERILGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRE 416
            .||||.|:|||||:|||.|||.:||:.|||||..|.||..:|:.|||||:.:::|:||||:|.|.
  Fly   172 CVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDNQALLQDPLYVGARI 236

  Fly   417 RRATGDLYDEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAV 481
            .|..|..|||.:||||.:.|:.||.|..|.|||||..||.:.|.||:..:|.||||||||.:..:
  Fly   237 PRVKGPEYDELVDEFMESAVKCFGNNTFIHFEDFATPNALKFLEKYQYKYCCFNDDIQGTGATGL 301

  Fly   482 AGLLASLKIKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRD 546
            |..:...:|...:|:|...||:|||.|||||||:..|.::|.|:..|||...|:::|..|::|.:
  Fly   302 AAFINVERITGRKLEDTVFLFVGAGSAALGIANMLAMELEVRGIPAEEATKNIYLMDVNGILTPE 366

  Fly   547 RPKGGLTEHKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFAL 611
            .|..  .|....|.:..||:..:...::|::|:||:||...||.||:|:|:.||..:|.|.:|.|
  Fly   367 SPNP--PEMGKIFIKSMEPMKDMMAVLKKLKPSVLVGATGVGGIFNEEVLKTMAKNHERPAVFPL 429

  Fly   612 SNPTSKAECTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLN 676
            ||||:.:|||||:|:|:|:||.:|.|||||.||..|.|::.|.|.||...|||:||..:.|....
  Fly   430 SNPTANSECTAEQAFTHTEGRVLFGSGSPFPPVVINGKRYRPAQANNCLTFPGIALAAITAKARY 494

  Fly   677 IPEQVFLVAAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKL 741
            :|.:||.|.:..||....::.|.:|:|:||:....:.:..:...:.:|...|.|:.|.|:|.:..
  Fly   495 LPNEVFSVVSHELARNTPQELLDEGTLFPPIKDAHNVAFNVGVAMTQYLIDNDLSNVYPKPDDIC 559

  Fly   742 AFIKAQMYDLDYPRSVPATY 761
            .|:|..:|..||..|:|.|:
  Fly   560 EFVKRSLYKFDYRNSLPTTW 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	231/534 (43%)
Menl-2	NP_001027424.2	PLN03129	8..573	CDD:215594	231/532 (43%)