Protein Alignment Men and Menl-1

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_001027428.1
• Gene: Menl-1 / 3772542
• FlyBaseID: FBgn0029154
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 250/594 - (42%)
• Similarity: 361/594 - (60%)
• Gaps: 26/594 - (4%)

  Fly   173 SYSSTSETNLEDKMS----KPDSKLDKYAQRDRLGLWGTGDNEVVGSLSGFTRLLDKRYSKGLAF 233
            |.|.|.::|.|...:    :|.|..|..    |:.:      |||.|        || .:|.|||
  Fly    16 SISKTHQSNCECSPNLIKIRPSSSHDTI----RVPI------EVVFS--------DK-CNKALAF 61

  Fly   234 THEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLSSDIA 298
            |.||||:|.|||::|..||...||:....:.....:.::.:|.||.:|.:..|||::..:|.::.
  Fly    62 TLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVH 126

  Fly   299 YMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWP-ETDVRAIVVTDGERILGL 362
            .::|::|||||||||..|.::::...|:.|:..|:||:..:|.||| ...|:||.||||:|||||
  Fly   127 AVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTDGQRILGL 191

  Fly   363 GDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLYDEF 427
            ||||||||||.|||:.||||||||.||..|||.||||||.:|:.|||||||||:.|..||.|..|
  Fly   192 GDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLYIGLRDERLKGDEYVCF 256

  Fly   428 IDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLKIKK 492
            :||||.|.|..||...||.|||||..|||..|::|:..:|.|||||||||:|.:.|||...:|.|
  Fly   257 VDEFMEAVVSTFGDQTLIHFEDFATPNAFMFLNRYQHCYCHFNDDIQGTAAVGLGGLLGIQRITK 321

  Fly   493 TQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTEHKL 557
            ..|:::.::|.|||.||:|||.|..|.:...||:|.:|...|:..|..||:|..|.  .:.:...
  Fly   322 KPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIYFYDQDGVLTTARK--SIPDILC 384

  Fly   558 HFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAECTA 622
            .||:..:...:|...|.:|:|::::||.:..|.|.::|:..||..:|.|.|||.||||.|:||||
  Fly   385 VFAKNMKETKSLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERPGIFAFSNPTIKSECTA 449

  Fly   623 EEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLVAAE 687
            |:||.::.|:.|:::||||.||.:|.|:..|||.||.:.||.:.|..:......:|:::||:||.
  Fly   450 EQAYKFSDGKAIYSAGSPFPPVEFNGKRLTPGQANNCFAFPALVLATMTVLATRMPDEIFLLAAH 514

  Fly   688 RLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMYDLD 752
            .|||..:.:::..|.:||.:......:..|..::.:|..:||.|....||.:...:|:...|.|.
  Fly   515 ELAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNLEPEDVEEYIEKNSYKLT 579

  Fly   753 YPRSVPATY 761
            |..|:..|:
  Fly   580 YGSSLAETW 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	237/544 (44%)
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	243/567 (43%)