Protein Alignment Men and Men-b

DIOPT Version :10

• Sequence 1: NP_524880.2
• Gene: Men / 47173
• FlyBaseID: FBgn0002719
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: XP_061503593.1
• Gene: Men-b / 1273984
• VectorBaseID: AGAMI1_003772
• Length: 626
• Species: Anopheles gambiae
• Alignment Length: 597
• Identity: 341/597 - (57%)
• Similarity: 441/597 - (73%)
• Gaps: 2/597 - (0%)

  Fly   165 QQQQQQLRSYSSTSETNLEDKMSKPDSKLDKYAQRDRLGLWGTGDNEVVGSLSGFTRLLDKRYSK 229
            :|....||:...|:........:...:.:..:..||...:  |||..|...:.|...|.|.|.:|
Mosquito    11 KQTVDALRTLVGTASPKKSLTKAATSAAVQAFQARDYHEV--TGDIIVPSMVQGIDHLRDPRLNK 73

  Fly   230 GLAFTHEERQQLGIHGMLPYVVREPSEQVEHCRALLARLDQDLDKYMYLISLSERNERLFYNVLS 294
            |||||.||||.|||||:.|...:...||:|.||..::|..:||:||:||:.|.:||||||:.::|
Mosquito    74 GLAFTLEERQILGIHGLQPARFKSQEEQLELCRISISRYQEDLNKYLYLVDLQDRNERLFFRLIS 138

  Fly   295 SDIAYMMPLVYTPTVGLACQRYSLIHQNAKGMFISIKDKGHIYDVLKNWPETDVRAIVVTDGERI 359
            .|:..|||:|||||||||||::.||::..:|:|::|.|:||::|||:||||.|||||||||||||
Mosquito   139 EDVEKMMPIVYTPTVGLACQKFGLIYRRPRGLFVTINDRGHVFDVLRNWPEPDVRAIVVTDGERI 203

  Fly   360 LGLGDLGANGMGIPVGKLSLYTALAGIKPSQCLPITLDVGTNTESILEDPLYIGLRERRATGDLY 424
            ||||||||.|||||||||:||||||||.|.|||||.:|||||.:.:||||||||||.:|..|..|
Mosquito   204 LGLGDLGACGMGIPVGKLALYTALAGIPPHQCLPIVIDVGTNNKDLLEDPLYIGLRHQRVQGKEY 268

  Fly   425 DEFIDEFMHACVRRFGQNCLIQFEDFANANAFRLLSKYRDSFCTFNDDIQGTASVAVAGLLASLK 489
            ||||||||.|.|:|:|||.|||||||.|.||||.|.|||:::|||||||||||||||||:||:.:
Mosquito   269 DEFIDEFMQAVVKRYGQNTLIQFEDFGNHNAFRFLDKYRNTYCTFNDDIQGTASVAVAGMLAAKR 333

  Fly   490 IKKTQLKDNTLLFLGAGEAALGIANLCLMAMKVEGLTEEEAKARIWMVDSRGVITRDRPKGGLTE 554
            |...::.|||.|||||||||:|||:|.:.||:.||...:||:.:|||.|..|::.:.||:|.|..
Mosquito   334 ITNKRISDNTFLFLGAGEAAVGIADLVVKAMQAEGTGLQEARDKIWMFDIDGLLAKGRPEGRLGG 398

  Fly   555 HKLHFAQLHEPIDTLAEAVRKVRPNVLIGAAAQGGAFNQEILELMADINETPIIFALSNPTSKAE 619
            ||.::|:.|..:...|:.|::|:|:|||||:|.||||..|||:.|...||.||||||||||||||
Mosquito   399 HKAYYAKDHGVMKNFADVVKEVKPSVLIGASAAGGAFTPEILQAMGQFNERPIIFALSNPTSKAE 463

  Fly   620 CTAEEAYTYTKGRCIFASGSPFAPVTYNNKKFYPGQGNNSYIFPGVALGVLCAGMLNIPEQVFLV 684
            |||:.||..|:|||||||||||.||.|..|.|..|||||:||||||||||:..|..:|||.:||:
Mosquito   464 CTAQAAYDNTEGRCIFASGSPFPPVQYGGKTFITGQGNNAYIFPGVALGVIVTGTHHIPEDMFLI 528

  Fly   685 AAERLAELVSKDDLAKGSLYPPLSSIVSCSMAIAERIVEYAYKNGLATVRPEPVNKLAFIKAQMY 749
            ||:.:|:.||:.||.|||||||||:|..|||.||..:..|||:.|||:..|||.:|.::|::.:|
Mosquito   529 AAQVVADHVSEADLEKGSLYPPLSAIKECSMDIAVGVTNYAYQKGLASTYPEPEDKKSYIESHLY 593

  Fly   750 DLDYPRSVPATY 761
            :.:|..::|.|:
Mosquito   594 NYNYQSAMPVTW 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Men	NP_524880.2	PLN03129	213..757	CDD:215594	329/543 (61%)
Men-b	XP_061503593.1	None