DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arg and Arg1

DIOPT Version :9

Sequence 1:	NP_524875.1	Gene:	arg / 46717	FlyBaseID:	FBgn0023535	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_038959286.1	Gene:	Arg1 / 29221	RGDID:	2150	Length:	335	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	122/324 - (37%)
Similarity:	190/324 - (58%)	Gaps:	19/324 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 REPEQSLG-------IIGVPFAKGQAKQGVELAPDLLRQSSLRQVLQSSHDGLVIRDYGNLQYAV 83
            :||..|:.       |||.||:|||.:.|||..|..||::.|.:.|:.:...  :||:|:|.: |
  Rat     7 QEPWMSMSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYN--VRDHGDLAF-V 68

  Fly    84 DEPLLQQQRVHYHHIRNYADFMACNRALIEQVKLMLVENTQFLAIGGDHAIGFGSVAGHLQHTPN 148
            |.|    ....:..::|.......|..|...|.......|..:.:||||::..||::||.:..|:
  Rat    69 DVP----NDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPD 129

  Fly   149 LSLVWIDAHADINLHSTSQSGNIHGMPVSFLLEQLRNTWQHA-GLQEIAPNCLPKDQLVYIGLRD 212
            |.::|:|||.|||...|:.|||:||.||:|||::|:..:... |...:.| |:....:|||||||
  Rat   130 LCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTP-CISAKDIVYIGLRD 193

  Fly   213 IDPYEAFILNKVGIRYYAMDTIDRVGVPKIIEMTLDALNPQNK--IHVSFDIDALDSNVAPSTGT 275
            :||.|.:|:..:||:|::|..:|::|:.|::|.|...|..:.|  ||:|||:|.||....|:|||
  Rat   194 VDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGT 258

  Fly   276 AVRGGLTLREGISIVEALRDTKRVQGVDLVEINPKLG-SERDVRTTVESGLEILKSMFGYRRSG 338
            .|.|||:.|||:.|.|.:..|..:.|:|::|:||.|| :..:|..||.:.:.:..|.||.:|.|
  Rat   259 PVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREG 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arg	NP_524875.1	Arginase	32..331	CDD:212515	114/309 (37%)
Arg1	XP_038959286.1	Arginase-like	21..315	CDD:212536	114/301 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340487
Domainoid	1	1.000	222	1.000	Domainoid score	I2501
eggNOG	1	0.900	-	-		E1_COG0010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3335
OMA	1	1.010	-	-		QHG56454
OrthoDB	1	1.010	-	-		D1179130at2759
OrthoFinder	1	1.000	-	-		FOG0001970
OrthoInspector	1	1.000	-	-		otm46467
orthoMCL	1	0.900	-	-		OOG6_102008
Panther	1	1.100	-	-	LDO	PTHR43782
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1288
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770