| Sequence 1: | NP_004989.2 | Gene: | MYO1E / 4643 | HGNCID: | 7599 | Length: | 1108 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_013827.1 | Gene: | MYO5 / 855136 | SGDID: | S000004715 | Length: | 1219 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 1171 | Identity: | 476/1171 - (40%) |
|---|---|---|---|
| Similarity: | 692/1171 - (59%) | Gaps: | 116/1171 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Human 3 SKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPY 67
Human 68 FGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRV 132
Human 133 SGGGTK-VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEK 196
Human 197 SRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETLHA 261
Human 262 MNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGINQDRLKEKLT 324
Human 325 SRQMDSKWGGKSESI-HVTLNVEQACYTRDALAKALHARVFDFLVDSINKAMEK-DHEEYNIGVL 387
Human 388 DIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIEN 452
Human 453 KVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDG 517
Human 518 FCERNRDVLFMDLIELMQSSELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPH 582
Human 583 YIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTK----AT 643
Human 644 WPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRK 708
Human 709 FVARK------------------KYVQMREEASDLLLNKKERRRNSI--NRNFIGDYIGMEEHPE 753
Human 754 ----LQQFVGKREKIDFA----DTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKE 810
Human 811 VLKRKIEIERILSVSLSTMQDD---IFILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLK 872
Human 873 FSNTLELKLKKENWGPWSAGGSRQVQFHQG---FGDLAVLKPSNKVLQVSIGPGLPKNS---RPT 931
Human 932 RRNTTQNTGY-SSGTQNANYPV------------------RAAPPPPGYHQNGVIRNQYVPYPHA 977
Human 978 PGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGR 1042
Human 1043 PKPQPKPKPQVPQCKALYAYDAQDT-DELSFNANDIIDIIKEDPSGWWTGRL--RGKQGLFPNNY 1104
Human 1105 V 1105 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MYO1E | NP_004989.2 | MYSc | 14..692 | CDD:214580 | 340/686 (50%) |
| MYSc_Myo1 | 33..679 | CDD:276829 | 322/654 (49%) | ||
| Actin-binding. /evidence=ECO:0000255 | 581..591 | 7/9 (78%) | |||
| Myosin_TH1 | 719..902 | CDD:283635 | 55/195 (28%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 919..966 | 20/68 (29%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 993..1053 | 21/59 (36%) | |||
| SH3_MyoIe_If_like | 1056..1107 | CDD:212761 | 18/53 (34%) | ||
| MYO5 | NP_013827.1 | COG5022 | 1..1186 | CDD:227355 | 476/1171 (41%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 643 | 1.000 | Domainoid score | I21 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0162 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 774 | 1.000 | Inparanoid score | I72 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S951 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000187 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm10096 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100187 | |
| Panther | 1 | 1.100 | - | - | O | PTHR13140 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2201 |
| SonicParanoid | 1 | 1.000 | - | - | X1588 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.800 | |||||