Protein Alignment l(3)04053 and ENTR1

DIOPT Version :10

• Sequence 1: NP_649414.1
• Gene: l(3)04053 / 46158
• FlyBaseID: FBgn0010830
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_016869707.1
• Gene: ENTR1 / 10807
• HGNCID: 10667
• Length: 484
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 107/516 - (20%)
• Similarity: 176/516 - (34%)
• Gaps: 160/516 - (31%)

  Fly   112 GARPKV------PQSASVSHMQPPDVNGSSASSRMKRSPRFSSFD----------SQASLAEYAS 160
            |.||..      |..|||          .....|..|.|| ..|.          |.:|..:.:.
Human    53 GIRPAFMCYVPSPVLASV----------GDTGERRGRRPR-GRFQFPRHVWHLRCSTSSSIDPSM 106

  Fly   161 CGGGTSSSSGGSQSQHRLRPDHRL--GHDAVQDALDNDDDDHVALAQVRNTNRHYDERIDDDIFP 223
            |...|:..:.|.|.:..|...|.|  |....:..:...|||            .:::..:.:.|.
Human   107 CRALTACQALGIQRRSPLLGAHSLVAGRPPPRQTVPVQDDD------------RFEDLEEANPFS 159

  Fly   224 ----------SASNQQPAVGSRYVPRSYSNYDM------PPHLPGPSSSPRRRPTGNRDQRPTRL 272
                      ..|.:.||  ||...:..|.:.:      ||...|......::|.   .:.||
Human   160 FREFLKTKNLGLSKEDPA--SRIYAKEASRHSLGLDHNSPPSQTGGYGLEYQQPF---FEDPT-- 217

  Fly   273 VLSAGPKMKLDLPLDTCNVAGGGAGGSAAAASALPDFVQDHLPDAWCAGQDALS------SPPNS 331
              .||..:..:...||     |.:|      :.||..::...|:...||....|      |.| |
Human   218 --GAGDLLDEEEDEDT-----GWSG------AYLPSAIEQTHPERVPAGTSPCSTYLSFFSTP-S 268

  Fly   332 PLVGAEASSGAVGLLPSSLAPRCSSAAALPGPTGEPTAGSTVKMLPDFLSDGSIIHSSQRLADVA 396
            .|.|.|:       |||.......|..:...|.|.|:|        ||...|      :.|.|..
Human   269 ELAGPES-------LPSWALSDTDSRVSPASPAGSPSA--------DFAVHG------ESLGDRH 312

  Fly   397 IGLPSNPIDSPPQEAEGTLQLS--TLRQENERLQRELQEARAELNLQTRRASEFEQQL--LQLSE 457
            :               .|||:|  .|:.||.:|:|:|.|.::....||......|::|  ..:.|
Human   313 L---------------RTLQISYDALKDENSKLRRKLNEVQSFSEAQTEMVRTLERKLEAKMIKE 362

  Fly   458 TS------------RRREALATTTNTQTTQH---LRRQLAQLEAELRSLRGSSGSSDCATGGVPV 507
            .|            .:...|.|....:...|   |:::::.|:|::.:.:
Human   363 ESDYHDLESVVQQVEQNLELMTKRAVKAENHVVKLKQEISLLQAQVSNFQ--------------- 412

  Fly   508 ATPGRDSEA-STSSGISAERPSRTQHLSRDLLRAA-DTAEQNLRQLLTGVENLRQMAASLE 566
                |::|| ....|.|.....:...::...||.. ::|:.:::||::|.|.|..:|..|:
Human   413 ----RENEALRCGQGASLTVVKQNADVALQNLRVVMNSAQASIKQLVSGAETLNLVAEILK 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)04053	NP_649414.1	COG4372	416..>570	CDD:443500	36/172 (21%)
ENTR1	XP_016869707.1	SMC_prok_B	<310..>482	CDD:274008	39/194 (20%)