Protein Alignment Gug and atn1

DIOPT Version :10

• Sequence 1: NP_001261581.1
• Gene: Gug / 46156
• FlyBaseID: FBgn0010825
• Length: 2007
• Species: Drosophila melanogaster
• Sequence 2: XP_002941264.2
• Gene: atn1 / 100486351
• XenbaseID: XB-GENE-6458762
• Length: 1129
• Species: Xenopus tropicalis
• Alignment Length: 1329
• Identity: 319/1329 - (24%)
• Similarity: 419/1329 - (31%)
• Gaps: 518/1329 - (38%)

  Fly   930 KSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQ----------------------- 971
            |....||..|.  .|..|::||..|..|:.:......|...:
 Frog    33 KKESVGPREER--RARGRASPGAISTSSSDSKSEKGRPSGKKGRMEDSVPKNSKRERVKDSSESE 95

  Fly   972 ------QFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSA 1030
                  |.::...||.:|.|     ||   ....:.|......|||.|:      .:.|...:::
 Frog    96 GEAGKTQKKAKMESPEVPRP-----PP---DDESLDGQSGNEDGGSDPR------DIDQDNRSTS 146

  Fly  1031 GPPSLQHGLHPGHQHSQLSVASSIP-PSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPP 1094
              ||    ||.|...|.   |||:| |.|.   |.....:|        |......:..|..|||
 Frog   147 --PS----LHSGDSESD---ASSVPSPKSF---PLYRGSSP--------PRPSSSPISEPTVLPP 191

  Fly  1095 ---------SMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRT--PSPAQ 1148
                     .:.|.||.|.    .|.|...|.||:                 .|.|:.  |.|||
 Frog   192 PSQAPQTATQIEPQAPRPY----QPTHLPQLYPSN-----------------GGLVKAGPPQPAQ 235

  Fly  1149 QPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPM 1213
            ..|           |||    |.:||.   |.|.|..||.|..::| ...:.|
 Frog   236 VKP-----------PPT----TPIAGL---GSPRPLGSPTAPASAP-TNCSSS------------ 269

  Fly  1214 AIHPHLAH-LPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTP- 1276
            |.:||::| |||........|.||   |...:|  ...|.|:.           |.||..|..|
 Frog   270 ASYPHVSHNLPPPPALRPLNASPG---LQSQVA--EKVGQPLP-----------PTSASLRYPPY 318

  Fly  1277 ----PSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSV 1337
                ||:.||.:.:..........              |.|::.::  .:.....|||||.|..
 Frog   319 PGQYPSNYPHPYPTQGKYNQPQPG--------------PHSSWGQS--GLNYGRGGGGPSYPQP- 366

  Fly  1338 GPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERD 1402
                 |..:..||..........|.....|...||||:..|..|   ||::..:.:.|:.::...
 Frog   367 -----PPQNGQAAGGGQNIAGGFPPPHHGSARAQSPLNNHPPHP---HPTTGGIQSPASQISVLH 423

  Fly  1403 RH---ALMRQQSPHMTPPPVSNASLMASPLSKMYAPQ--PGQRGLGTSPPPHLRPGASPPVIRHP 1462
            .|   :..|.|||:             .||:..:.|.  | .||...:|..:|.||::|.....|
 Frog   424 SHGGASGTRGQSPN-------------HPLNNAHHPHILP-NRGRSPTPQSNLTPGSTPQSGHQP 474

  Fly  1463 QMPLPLPLIAP--------------GGG--------------IPQIGVHPGQSPYPHPL------ 1493
            ...||..:|:|              ||.              :||.....|...||.|.
 Frog   475 AHILPGGIISPNPPPQNNTQLTSSTGGSARGQSPAPTNTPHLLPQSNSSSGSMAYPAPAEPSNPP 539

  Fly  1494 -LHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQD 1557
             .||  .|.||..|  |...|.|....:|.|      |.|            |.:|.||
 Frog   540 STHP--VYQPHSSP--SVCQYPPSSQTYPNY------PFQ------------GYKGAPP------ 576

  Fly  1558 EQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPG 1622
                                 ||...:...|...:||..|.:.||.|               ..|
 Frog   577 ---------------------AAPPYKTAPPPPYKPGSFPASTPPPP---------------SQG 605

  Fly  1623 TPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHP 1687
            .....||...|.      ||..|...|                                    .|
 Frog   606 FKEASPPATAPA------PQPVPQPVP------------------------------------QP 628

  Fly  1688 TEPLPIDIEPDPEPEI----PSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRT 1748
            ..|.|:.|:.:|..|:    .||...: ..|||..|..||..|.||||.|.:|:||| ||||.||
 Frog   629 PAPAPVQIKQEPPEEVEGEGESPVPPV-SSPSPPPKLVDTPSHASQSARFNKHLDRG-YNSCCRT 691

  Fly  1749 DLIFKPVADSKLARKR-----------EERDRKLAEKERERRQQQQQQ--------------QQQ 1788
            ||.|.|:..|||::||           |:|.|:..|:||||.::.::.              .|.
 Frog   692 DLYFVPLEGSKLSKKRSEQIERARRESEQRAREERERERERERELERNTKLDSRSHDCPQLCTQP 756

  Fly  1789 QQQQQAAAAQQAAQQAKMKAELKPPYA----------DTPALRQLSEYARPHVAFSPVEQMV--- 1840
            .....:.|....:..|......:||.|          ||||||.||||||||| .||..:..
 Frog   757 PSHHPSLALPSPSSAANRPPHFEPPGAVAAVPPYLGPDTPALRTLSEYARPHV-LSPAGRAQPPG 820

  Fly  1841 -PYHHPM-------------------GPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHP 1885
             |.|||.                   .|...||||.| :...........|||         :||
 Frog   821 HPPHHPFYLPLGDPLLAYNLPAVFASDPARAERELRE-RLKPGYEVKPGELDP---------LHP 875

  Fly  1886 SQFPLYANP----AISQMERERLGIPP--------PHHVG-------------------LDPG-- 1917
            |..||...|    |..|......|:||        |:|.|                   ..||
 Frog   876 SSIPLPPPPPHHHAPHQPPPSAAGVPPQMALHPAFPYHHGQHAHAHALERERLALGAAAAGPGGA 940

  Fly  1918 ------------------------EH----------------MIRLTREYHAHSHTHLHLPLHPQ 1942
                                    :|                |:.:|..:|.|||.|.||.||.|
 Frog   941 QGATAAAGAGRGELSYAERLAAERQHAERVAALSGDPLARLQMLNVTPHHHQHSHIHSHLHLHQQ 1005

  Fly  1943 PQPPEAGFQLPPNVG-----------QYPR---PNMLIPREPH-SDVLLR--------------- 1977
            .....|...:.|.:.           .||.   ||.|||...| ||||.:
 Frog  1006 DAIHAASAAVHPLMDPLASGSHLTRIPYPATTLPNTLIPHALHDSDVLRQQIFASPYRDLPSALS 1070

  Fly  1978 --MSYADQLQ--YLQAAEFQRQSLHDQYF 2002
              :|.|.|||  :.|:||.||.:|..|::
 Frog  1071 APLSAAHQLQAMHAQSAELQRLALEQQHW 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:460214
		SANT_MTA3_like	126..171	CDD:212559
		PHA03247	<856..1289	CDD:223021	96/405 (24%)
		Atrophin-1	<1408..>1857	CDD:460830	141/547 (26%)
atn1	XP_002941264.2	Atrophin-1	16..1127	CDD:460830	319/1329 (24%)