Protein Alignment vlc and dlgap2a

DIOPT Version :10

• Sequence 1: NP_524868.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_073784647.1
• Gene: dlgap2a / 557621
• ZFINID: ZDB-GENE-101215-1
• Length: 1738
• Species: Danio rerio
• Alignment Length: 699
• Identity: 153/699 - (21%)
• Similarity: 254/699 - (36%)
• Gaps: 200/699 - (28%)

  Fly     3 RSLDSIGSCSLDVDADSSDISDT------------SGSLNFPTPVSVRDITRE---FTANLRERC 52
            |..|...|||.:.|..:...|||            ||.|...|..|....:.|   |...:....
Zfish  1112 REEDGAESCSEEKDGQNVASSDTMINFAVQSDAVDSGPLESETLFSAVLCSIESDTFDPEVTSMD 1176

  Fly    53 VPNL----PPQPQHKTPAYVESRSSELEHMVLSPAIVECDQEPSSNDFDETSAENSQEAPEKKPS 113
            .|..    ||......||.|...:..|  :.|..|:.....|.|.|...:.:|..|  :|...||
Zfish  1177 EPTTQGSNPPGLATIDPATVHPFNLSL--LELQSALDVSKSETSDNGSPKGTAAIS--SPSYSPS 1237

  Fly   114 -----YLNLACCVNGYSNLTTYDSKIRQDINKSREVSPIRPSTSSLQYCKR-----NHFLATPTL 168
                 ::.......|           ||.:::|..:....||:.|:....:     .:..:|||.
Zfish  1238 RRDFLWIRWQRKTRG-----------RQPMSRSARIQFHLPSSGSVDRPSQQPPAVTYTPSTPTY 1291

  Fly   169 HSMPSPATKCKPIEPNNNSNDSSGNFSSGSGHSNGNGSFIKQRVERLYGPGALAQGFY------- 226
            ...|      .|:.|.:.|.......:..|..|          .:..|..|.||:||:
Zfish  1292 KRTP------PPVPPRSTSKPLISITAQSSTES----------TQDAYHEGQLARGFWGSDGSSL 1340

  Fly   227 ------------------------------SPKKHGQSPSNAA-------------------GRS 242
                                          :.|:|..:.|:::                   .||
Zfish  1341 SLGRALYNSTDSLDSAKAVTIAMEAAAMAMAGKRHPSTDSHSSVMTCDKAVLVSKAEEYLKTPRS 1405

  Fly   243 ERG-QVE--IDSLQGSELARKFK----QLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNG 300
            ..| |||  .||...|:.:|:::    |:...:..|.|::      |.|.||.:...|...|
Zfish  1406 SIGIQVEAATDSECESKGSREYQSVGIQVEDERRQGRFKR------SNSVTAAVQADLELEG--- 1461

  Fly   301 DLDLPVFRHLSQEF-----RAQLPTVSPKRGAPRSCMA-------PDVLLVDNESSPDHGPTDEV 353
               .|:......:|     |...|:...:.||.|:...       .|........||...|...:
Zfish  1462 ---FPLMEDKGLQFGGGFQRHSEPSTPTQYGAVRTVRTQGLFSYREDYRTPTEPPSPQRSPEPWL 1523

  Fly   354 DHESTKMDKLASEEYISTSNISV------------EAVVKDGNFFLKILKEEQSRLLVLAALAEK 406
            :.        :..|.|:|..::|            .:..:||::|:::|..|..::       |.
Zfish  1524 EP--------SPREPIATVAVTVTPPQPSDSGRASPSCRRDGSWFMQLLHTETKKM-------EG 1573

  Fly   407 YADAL---STNPDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQG 468
            :...|   :...|:||:..|.:|||.|.|:||:|||.:||..||..||:.|...: ||: .||.|
Zfish  1574 WCKELEGEAEENDLSEEILGKIRSAVGSAQLLMSQKFQQFYWLCQQNLDPSAMPR-PTS-QDLAG 1636

  Fly   469 FWDMVYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKAS 533
            |||::.|.::.|.|.|.:::|:|||||::....|...|.  .:|.||::.|   |::.|::....
Zfish  1637 FWDLLQLSIDDVTSKFNELQKIKSNDWRLIDSPVKKLPP--PVPKKTLRKS---VTREKSLDLPD 1696

  Fly   534 SVRVNGSAPPPPNSAAALKREAQRKLLLEMKRQRREAMTAAAKLNPINV 582
            ..|:                ||:|:|:...:.......:|:.:.:.|.:
Zfish  1697 RQRI----------------EARRRLMAAKRAASFRQNSASERADSIEI 1729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_524868.1	GKAP	<381..>496	CDD:460897	45/117 (38%)
dlgap2a	XP_073784647.1	None