Protein Alignment vlc and dlgap5

DIOPT Version :10

• Sequence 1: NP_524868.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001004592.1
• Gene: dlgap5 / 447853
• ZFINID: ZDB-GENE-040912-160
• Length: 909
• Species: Danio rerio
• Alignment Length: 656
• Identity: 146/656 - (22%)
• Similarity: 245/656 - (37%)
• Gaps: 183/656 - (27%)

  Fly    42 REFTANLRERCVPNLPPQPQHKTPAYVESRSSELE-HMVLSPAIVECDQEPSSNDFDETSAENSQ 105
            ||...|:| |.:..||                |:: .|..|..:...|:.|.:    :|::::|.
Zfish    34 REKIQNMR-RHLDRLP----------------EIDLSMDTSTLMATQDKAPKT----KTASDSSD 77

  Fly   106 EAPEKKPSYLNLACCVNGYSNLTTY-DSKIRQDINKSRE------------------------VS 145
            .|.|:|             ..|..| ::||.|...:.||                        .:
Zfish    78 AAEERK-------------KMLARYKENKILQKEKEKREKEKKGVFKVGLYKPQPLGYLPSNTAA 129

  Fly   146 PIRPSTSSLQYCKR-------NHFLATPTLHSMPSP----ATKCKPIEPNN---NSNDSSGNFSS 196
            |.|...:.:....|       |..||... |::|..    :|...|.:.|.   .|..:....:.
Zfish   130 PGRAKATEMNQSTRMTRSMVQNQKLAVER-HAVPKKVECLSTARAPAKENRKPLTSTKTRATTAE 193

  Fly   197 GSGHSNGNGSFIKQRVERLYGPGALAQGFYSPKKHGQSPSNAAGRSERGQVEIDSLQGSELARKF 261
            ....:....|..|...:.:..|.|..:|   ||........||..|.||:|    :||:..|...
Zfish   194 PPVRAQTTRSAAKTAPDAVVKPVADTRG---PKTRSAVKYPAAPSSGRGKV----VQGNMKANVE 251

  Fly   262 KQLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSP--------------GLNGDLDLPVF----- 307
            .:.:..||              :...:::||..:|              ||.....:|:.
Zfish   252 NKPAEIKD--------------TAVDKVEEPKAAPASFAPQGFVFQPPVGLRSFEPVPLSPSSAN 302

  Fly   308 RHLSQEFRAQL------PTVSPKRGAPRSCMAPDVLLVDNESSPDH---GPTDEVDHESTKMDKL 363
            ..||..|.:::      |: .||.....|...|.|    :...|||   .|:.....::....:.
Zfish   303 AFLSPSFNSEVSMEPAFPS-PPKPVVSFSSPPPSV----SAHMPDHPISPPSVSSPLQAQSFPQP 362

  Fly   364 ASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADALSTNPDISEDTFGLLRSA 428
            :::...|.|:.|:|. ..|..:|...:..|..||..|:.|.|...|..|    |.|:....:|:|
Zfish   363 STDAAPSPSSASMEP-QHDVAYFRAAMASETERLTGLSELWESRFDDAS----IPEEMRDRMRTA 422

  Fly   429 SGKARLLVSQKMKQFEGLCHN-NLNRSPEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKS 492
            .|:||||:.::..||.||..: :..|.  :|. ||..||||||||||.|||.|:..|:.:::.::
Zfish   423 VGQARLLMKERFGQFNGLVDDCDFKRG--EKI-TTCTDLQGFWDMVYFQVEDVNKKFSALKEAEA 484

  Fly   493 NDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRVNGSAPPPPNSAAALKREAQR 557
            .|||.:.:.|..:        :.:|...|      ..|||::    |..    .:|||..|.|..
Zfish   485 RDWKEEVKPVTKK--------RVVKKPPV------VAGKAAA----GGG----GNAAAKSRLAAI 527

  Fly   558 KLLLEMKRQRREAM---------TAAAKLNPI----------NVDADPDVPGIIGDSC----ANP 599
            |..::.|:..::|.         :::..:.|:          .|::....|..:..||    ::|
Zfish   528 KAAMKAKQAEQKATETSDKPQEDSSSVSVAPVQSVVFHGGFFQVESPVKTPAAVRRSCRGVVSSP 592

  Fly   600 SVSNGS 605
            ||:..|
Zfish   593 SVTKFS 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_524868.1	GKAP	<381..>496	CDD:460897	43/115 (37%)
dlgap5	NP_001004592.1	PHA03247	<125..373	CDD:223021	51/274 (19%)
		GKAP	<362..506	CDD:460897	52/165 (32%)
		PHA03247	<547..671	CDD:223021	9/52 (17%)