Protein Alignment vlc and dlgr-1

DIOPT Version :10

• Sequence 1: NP_524868.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001337304.1
• Gene: dlgr-1 / 189142
• WormBaseID: WBGene00020970
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 143/624 - (22%)
• Similarity: 226/624 - (36%)
• Gaps: 194/624 - (31%)

  Fly     3 RSLDSIGSCSLDVDADSSDISDTSGSLNFPTPVSVRDITREFTANLRERCVPNLPPQP------- 60
            ||..|.|:.:..::..|:..||...:|                          |||:|
 Worm   107 RSSSSRGASTDSLNTTSNGFSDGGSNL--------------------------LPPKPNRIGCAA 145

  Fly    61 ---QHKTP-AYVESRSSELEHMVLSPAIVECDQEP----SSNDFDETSAENSQEAPE--KKPSYL 115
               |.:|. .:|.||.:. ..:.|:......::.|    |.||....:|..|.:.||  :.||||
 Worm   146 TGAQSETDLRFVTSRDTH-SSIPLNEPFGFGEKSPRAFMSENDLSAGAAGASTDFPEVTRTPSYL 209

  Fly   116 NLACCVNGYSNLTTYDSKIRQDINKSREVSPIRP----STSSLQYCKRNHFLATPTLHSMPSPAT 176
            .::|.:|||:          :..||| :::||.|    ||....:.:|...:.:......|:|..
 Worm   210 RISCALNGYT----------KSPNKS-DLTPIAPHPPVSTMGESFVERRSRMFSQPQQRNPAPGF 263

  Fly   177 KCKPIEPNNNSNDSSGNFSSGS--------------GHSN--GNGSFIKQRVERLYGPGALAQGF 225
            . .|:.|...|:.|:.:....|              .|::  ||.:.|.|.:..|.
 Worm   264 S-SPLPPTTVSSQSASSEIECSTPIVPLKNARLNTLQHTSEMGNHASIPQPIRDLI--------- 318

  Fly   226 YSPKKHGQSPSNAAGRSERGQVE-------IDSLQGSELARKFKQLSPSKD-YGEFRKKMQKKCS 282
               .|..|....:|.::|:..:|       |.:.|.:     |.::...|| .|...:|...|.|
 Worm   319 ---SKFNQLDLCSAHKNEKEGIENIEPHKFIINQQPA-----FDEIDLKKDSNGNDDEKKDLKIS 375

  Fly   283 QSTTARIDEPLHSPGLNGDLDLPVFRHLSQEFRAQLPTVSPKRGAPRSCMAPDVLLVDNESSPDH 347
                  ||....| |::|                                          |||..
 Worm   376 ------IDAESDS-GISG------------------------------------------SSPAS 391

  Fly   348 GPTD-EVDHESTKMDKLASEEYISTSNISVEAVVKDGNFFLKILKEEQSRLLVLAALAEKYADAL 411
            ...: ::..|..|.|:  .||..:||..|      :|:.| ::|.::     |.|.|..| .:|.
 Worm   392 SKKNIDISKEEPKQDE--EEEVTTTSTPS------NGHEF-QLLHDK-----VKAQLQTK-MNAA 441

  Fly   412 STN----PDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRSPEDKFPTTLDDLQGFWDM 472
            ||:    .|..|.....||:|.|.|.|||.:|..:|..|...|||...:|..|.|:.||:|||..
 Worm   442 STDLEHADDYPEKCSDSLRAAHGNAHLLVRKKFSKFNELIGKNLNPIADDPMPVTVQDLEGFWVT 506

  Fly   473 VYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDLHTIPTKTIKPSKVGVSQVKTVGKASSVRV 537
            :.::::.:...|..:|:.::.:|...|....::.| .|.....|.|            |...|..
 Worm   507 IDMELKGILKEFTKVEQYRAANWDPSAVKEEEEID-STTNRPPIAP------------KTRPVTA 558

  Fly   538 NGSAPPPPNSAAALKREAQRKLLLEMK---RQRREAMTA 573
            ...||        :..|..||.|.|.|   .|||..|.|
 Worm   559 KKKAP--------IVSEETRKKLAEQKALAEQRRAEMRA 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_524868.1	GKAP	<381..>496	CDD:460897	36/118 (31%)
dlgr-1	NP_001337304.1	GKAP	<446..598	CDD:460897	47/165 (28%)