Protein Alignment vlc and vlc

DIOPT Version :10

• Sequence 1: NP_524868.1
• Gene: vlc / 46078
• FlyBaseID: FBgn0259978
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: XP_061518476.1
• Gene: vlc / 1279945
• VectorBaseID: AGAMI1_012862
• Length: 1043
• Species: Anopheles gambiae
• Alignment Length: 1072
• Identity: 270/1072 - (25%)
• Similarity: 358/1072 - (33%)
• Gaps: 519/1072 - (48%)

  Fly     1 MDRSLDSIGSCSLDVDADSSDISDTSGSLNFPTPVSVRDITREFTANLRERC---VPN------- 55
            ||||:||||||||||||||:|.|||||.|||.||:|.:||||||||.::|||   |.|
Mosquito     1 MDRSVDSIGSCSLDVDADSTDFSDTSGELNFLTPISGKDITREFTAGIKERCMLPVINCQAVTSV 65

  Fly    56 LPPQPQHKTPAYVES---RSSELEHMVLSPAIVECDQEPSSNDFDETSAENSQEAPEKKPSYLNL 117
            |.|...|.:.....:   ...:.:...|.|.:      ..:.|...|:|.|      ||||||||
Mosquito    66 LDPVTGHISTVLTTTTAPNGQQQQQQALQPLL------SGTGDSSPTAATN------KKPSYLNL 118

  Fly   118 ACCVNGYSNLTTYDSKIRQDINKSREVSPIRPSTSSLQYCKR-----NHFLATPTLHSMPSPATK 177
            ||||||||||||||||:||||||||||||.||..::|.|.:.     .|.||.|||..:....|
Mosquito   119 ACCVNGYSNLTTYDSKLRQDINKSREVSPSRPIIATLHYNRTETGAGGHLLAAPTLSYVSMNNT- 182

  Fly   178 CKPIEPNNNSNDSSGNFSSGSGHS----------------------------------------- 201
                 .|||:|:::.|:|:.:|.:
Mosquito   183 -----INNNNNNNNNNYSASTGGNRMLKMNGAGVVNGGAAGRMRGMNGSILSPPSGGADMTDNVG 242

  Fly   202 --NGNG-----------------------------------SFIKQRVERLYG------------ 217
              ||||                                   |||:||||:|||
Mosquito   243 MFNGNGSFAGSMRTKVISSQSQISSHARDEATAQLLMTPKKSFIQQRVEKLYGASEVVVLNKQNY 307

  Fly   218 --------------------PGAL------------AQGFYSPKKHGQSPSNAAGRSERG-QVEI 249
                                ||.|            .|..:.|..:|.:.:..|..:..| .|..
Mosquito   308 SSSERKYLNNIANDNTSGGAPGKLIHHSSTAQAGQQQQHHHHPMGNGTARNGVANGAAGGLHVTN 372

  Fly   250 DSLQGSEL-ARKFKQLSPSKDYGEFRKKMQKKCSQSTTARIDEPLHSPGLNGDLD-LPVFRHLSQ 312
            ....|..| ....|||:.:.:               .|:..||        .|:: |||.|||..
Mosquito   373 GGTNGGSLHDENGKQLNGAAE---------------VTSGNDE--------ADVESLPVLRHLRP 414

  Fly   313 EFRAQLPTVSPKRGAPRSCMAP----------------------DVLLV----------DNESSP 345
            ||||||...|||: .|:....|                      :|.|.          .|.|:.
Mosquito   415 EFRAQLQIFSPKK-MPKPAAPPANRTTAVNGSAATHANGNTAEENVTLTTGPKRYTQSNGNSSNA 478

  Fly   346 DHGP-------TDEVDHESTKMDK-------------------------LASEEY---------- 368
            ||..       .:|.||.:|..::                         :|.||.
Mosquito   479 DHLEQQQHSLVREEQDHRTTVTNRSTMVVKNARISSHTTTTSSSTNGRIVAEEEEEENALLTSNH 543

  Fly   369 ----------------------------------------------------------------- 368
                                                                             
Mosquito   544 HHSNATSARSSTITEAKQQQHTTGVVTEQHHHETASQSRSSSTDMSTTTTTTKTSMAAVTSSTTV 608

  Fly   369 ----------------------------------------------------------------- 368
                                                                             
Mosquito   609 IVEEKMRSLVVVSPSSATAADNGVGRMSTADGGNAIATAAATVVPDEPKPTTVVAASVIENGVQN 673

  Fly   369 --------------------------------------------------------------IST 371
                                                                          ::.
Mosquito   674 GVRQCSDTITNGLESVVPAVSVKKEEVLVVGGGEIVNCDNSSQFDADNMRTANGGSTVVMEPVAP 738

  Fly   372 SNISVEAV----------------------------------------------VKDGNFFLKIL 390
            |:|::.||                                              |.|||.||:||
Mosquito   739 SSITLPAVATMADFVHPVVEGGIQSNGKPIEVTTNGQGSNDSSFGSSSSSNNNIVLDGNHFLRIL 803

  Fly   391 KEEQSRLLVLAALAEKYADALSTN-PDISEDTFGLLRSASGKARLLVSQKMKQFEGLCHNNLNRS 454
            |.||:||..:|...|:..:.|..: .:..||..|.:..|.||||||.||||||||.||:.|||:|
Mosquito   804 KTEQNRLKAMADEVEQEINLLKADGVEFGEDINGYILVAVGKARLLCSQKMKQFEDLCYTNLNQS 868

  Fly   455 PEDKFPTTLDDLQGFWDMVYLQVEHVDSIFADIEKLKSNDWKVKAQSVADQPDLH----TIPTKT 515
            |::||.||.:||:||||||.|||.:||:.||:|:..:.|.|:..|......|..:    ...||.
Mosquito   869 PDEKFQTTGEDLRGFWDMVMLQVNNVDASFAEIDSFRKNGWRKPAPKSPPPPARNGTAGATRTKL 933

  Fly   516 IK-PSKVGVSQVKTVGKASSVRV----NGSAPPPPNSA-AALKREAQRKLLLEMKRQRR----EA 570
            :| |.|.|       |.|:...|    ||......::| ||.|||||||.|:||||:::    :.
Mosquito   934 VKRPYKTG-------GTANGTTVTDGSNGVEAKKASAALAAAKREAQRKQLMEMKRKQKLANSQQ 991

  Fly   571 MTAAAKLNPINVDADPDVPGIIGDSCANPSVS 602
            .||.....|.:.:......|:.|...:|.|.:
Mosquito   992 QTAVEIFAPASDEPAAQQNGVGGGDDSNCSTA 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vlc	NP_524868.1	GKAP	<381..>496	CDD:460897	61/115 (53%)
vlc	XP_061518476.1	None