DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phb2 and PHB6

DIOPT Version :9

Sequence 1:	NP_001097372.1	Gene:	Phb2 / 46038	FlyBaseID:	FBgn0010551	Length:	338	Species:	Drosophila melanogaster
Sequence 2:	NP_001077924.1	Gene:	PHB6 / 816575	AraportID:	AT2G20530	Length:	286	Species:	Arabidopsis thaliana

Alignment Length:	286	Identity:	155/286 - (54%)
Similarity:	216/286 - (75%)	Gaps:	9/286 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KLGKGGPPGLGIGLKVLAAV---GAAAYGVSQSLYTVEGGHRAIIFSRLGGIQSDIYSEGLHVRI 73
            |:.||  ||.|    |:|||   |.:.||.:.:||.|:||||||:|:||.||:..:|.||.|:.|
plant     7 KVPKG--PGGG----VIAAVVIGGLSLYGATHTLYNVDGGHRAIVFNRLVGIKDKVYPEGTHLMI 65

  Fly    74 PWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSIC 138
            |||:.|||||:|::|..:.|.:||:||||:.|.||||:||.:..||.:::.||.:|.|:|||||.
plant    66 PWFERPIIYDVRAKPYLVESTSGSRDLQMVKIGLRVLTRPMADQLPEVYRSLGENYRERVLPSII 130

  Fly   139 NEVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSLTELSFGKEYTAAIEAKQV 203
            :|.||:|:|::|||||||||:.||..|||.|..||.:|:|.|||||:|.|:||||:|||||.|||
plant   131 HETLKAVVAQYNASQLITQRESVSREIRKILTLRAANFHIALDDVSITGLTFGKEFTAAIEGKQV 195

  Fly   204 AQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASS 268
            |.|||:||.|.||:|:|:|:..:::|||||::|:::|.|:..|.|:|.|||:.||:.||:||:.|
plant   196 AAQEAERAKFIVEKAEQDKRSAVIRAEGEAKSAQLIGQAIANNQAFLTLRKIEAAREIAQTISRS 260

  Fly   269 QNKVYLSADSLMLNIQDSGFDDMTEK 294
            .||||||::.|:||:|....|...:|
plant   261 ANKVYLSSNDLLLNLQAMDLDVKPKK 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	114/193 (59%)
PHB6	NP_001077924.1	SPFH_prohibitin	34..228	CDD:259799	114/193 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	224	1.000	Domainoid score	I690
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5263
Inparanoid	1	1.050	311	1.000	Inparanoid score	I737
OMA	1	1.010	-	-		QHG63567
OrthoDB	1	1.010	-	-		D1089994at2759
OrthoFinder	1	1.000	-	-		FOG0002111
OrthoInspector	1	1.000	-	-		otm2842
orthoMCL	1	0.900	-	-		OOG6_101763
Panther	1	1.100	-	-	O	PTHR23222
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1399
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840