Protein Alignment Phb2 and unc-24

DIOPT Version :10

• Sequence 1: NP_001097372.1
• Gene: Phb2 / 46038
• FlyBaseID: FBgn0010551
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001355386.1
• Gene: unc-24 / 177594
• WormBaseID: WBGene00006761
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 341
• Identity: 65/341 - (19%)
• Similarity: 125/341 - (36%)
• Gaps: 89/341 - (26%)

  Fly     7 NDLAGKLGKGGP--PGLGIG-------------------LKVLAAVGAAAYGVSQSLYTVEGGHR 50
            ||| .|:|..||  .|:.:|                   :|.|:|:....:.|| .|:.|.....
 Worm    63 NDL-DKMGYMGPARQGMMLGNKYGNFTYTRDYGVNMEDDIKPLSAIELLIFCVS-FLFVVMTMPL 125

  Fly    51 AIIFSRLGGIQSDIYSEGLHV-RIPWFQYPIIYDIRSRPRKISSPTGSKDLQMINISLRVLSRPD 114
            :::|: |..|.:   ||.|.| |:            .|.:|...|..:..:..|:.:.:|.....
 Worm   126 SLLFA-LKFIST---SEKLVVLRL------------GRAQKTRGPGITLVIPCIDTTHKVTMSIT 174

  Fly   115 SLNLPYLH--------KQLGVDYDEKV---LPSICNEVLKSVIAKFNASQLITQRQQVSLLIRKE 168
            :.|:|.|.        .:||.....|:   :.::|....::...:..|:.::.:......:...|
 Worm   175 AFNVPPLQIITTDRGLVELGATVFLKIRDPIAAVCGVQDRNASVRTLANTMLYRYISKKRICDDE 239

  Fly   169 LVERARDFNIILDDVSLTELSFGKE------YTAAIEAKQVAQQEAQRAV------FFVERAKQE 221
            |......|.:.:.||.::::...||      ...:..||..|.|:..:.:      |..|.|.:|
 Worm   240 LGSFTCQFGVEITDVEISDVKIVKEGENMGMSALSSVAKSDAGQQLWQVIGPVFEDFAKECAAEE 304

  Fly   222 KQQKIVQAEGEAEAAKMLGLAVKQNPAYLKLRKLRAAQSIARTIASSQNKVYLSADSLMLNIQDS 286
            |                    .|:|...:.|..: .:.|.|.|...:.|...:..|.| :::...
 Worm   305 K--------------------AKENAPLVDLSDV-PSTSAAGTSTDTPNIPSIDIDHL-ISVASL 347

  Fly   287 GFDD----MTEKVYKI 298
            ..|:    :..:|::|
 Worm   348 AMDEHLVRLIGRVFQI 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	39/217 (18%)
unc-24	NP_001355386.1	SPFH_like	146..263	CDD:473137	18/116 (16%)
		SCP2	357..439	CDD:442486	2/7 (29%)