Protein Alignment Phb2 and Nphs2

DIOPT Version :10

• Sequence 1: NP_001097372.1
• Gene: Phb2 / 46038
• FlyBaseID: FBgn0010551
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_569723.1
• Gene: Nphs2 / 170484
• MGIID: 2157018
• Length: 385
• Species: Mus musculus
• Alignment Length: 339
• Identity: 75/339 - (22%)
• Similarity: 132/339 - (38%)
• Gaps: 91/339 - (26%)

  Fly    18 PPGLGI--GLKVLAA----VGAAAYGVSQSLYTVEGGHRAIIFSRLGG-IQSDIYSEGLHVRIPW 75
            |.|||.  .|.|||:    :....:.:...:..|:...|.||| |||. :.......||...:|.
Mouse    97 PSGLGACEWLLVLASLIFIIMTFPFSIWFCIKVVQEYERVIIF-RLGHLLPGRAKGPGLFFFLPC 160

  Fly    76 FQYPIIYDIRSRPRKIS-SPTGSKDLQMINISLRVLSRPDSLNLPYLHKQLGVDYDEKVLPSICN 139
            .......|:|.:..:|. ....:||:.::.|......|.::.:|  |...|.  :..|.:..:..
Mouse   161 LDTYHKVDLRLQTLEIPFHEVVTKDMFIMEIDAVCYYRMENASL--LLSSLA--HVSKAIQFLVQ 221

  Fly   140 EVLKSVIAKFNASQLITQRQQVSLLIRKELVERARDFNIILDDVSL--------TE-----LSFG 191
            ..:|.::|..:.::::.:|:.:           |:|..:.||.|:.        ||     |..|
Mouse   222 TTMKRLLAHRSLTEILLERKSI-----------AQDVKVALDAVTCIWGIKVERTEIKDVRLPAG 275

  Fly   192 KEYTAAIEAKQVAQQEAQRAVFFVERAKQEKQQKIVQAEGEAEAAKMLGLA---VKQNPAYLKLR 253
            .:::.|:||      ||||          :.:.:::.||||..|::.|.:|   :...||.::||
Mouse   276 LQHSLAVEA------EAQR----------QAKVRVIAAEGEKAASESLRMAAEILSGTPAAVQLR 324

  Fly   254 KLRAAQSIARTIASSQNKVYLSADSLMLNIQDSGFDDMTEKVYKIGTGLPKDWLDARKMASKVAQ 318
            .|...||::                             |||...:...||.|      |.|.::.
Mouse   325 YLHTLQSLS-----------------------------TEKPATVVLPLPFD------MLSLLSS 354

  Fly   319 PAEKEKNVGNVASS 332
            |..:.:...|..||
Mouse   355 PGNRAQGSINYPSS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phb2	NP_001097372.1	SPFH_prohibitin	42..236	CDD:259799	45/208 (22%)
Nphs2	NP_569723.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64
		SPFH_podocin	124..346	CDD:259809	59/282 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..385		3/12 (25%)