DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bka and UTP23

DIOPT Version :9

Sequence 1:	NP_524867.2	Gene:	Bka / 46032	FlyBaseID:	FBgn0010520	Length:	200	Species:	Drosophila melanogaster
Sequence 2:	NP_115710.2	Gene:	UTP23 / 84294	HGNCID:	28224	Length:	249	Species:	Homo sapiens

Alignment Length:	147	Identity:	39/147 - (26%)
Similarity:	69/147 - (46%)	Gaps:	8/147 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 TQQSSAL----FFQYNTQLGPPYHIVLDTNFINFSIKNKLDIVQGMMDCLYAKCIPYISDCVRAE 112
            |:|..|.    ||:.|..:..||.|:||..|...:::.::.:.:.:...|..:.....:.||..|
Human     4 TRQKHAKKHLGFFRNNFGVREPYQILLDGTFCQAALRGRIQLREQLPRYLMGETQLCTTRCVLKE 68

  Fly   113 LEKLGNKYKLALRIISDPRFERLPCLHKGTYADDCLVERVRQ---HKCYIVATNDKDLKNRIRKI 174
            ||.||.....|..|....:....|.........:||:..|.:   |. |.|||.|::|..:::|.
Human    69 LETLGKDLYGAKLIAQKCQVRNCPHFKNAVSGSECLLSMVEEGNPHH-YFVATQDQNLSVKVKKK 132

  Fly   175 PGVPIMYVAAHKYAIER 191
            ||||:|::..:...:::
Human   133 PGVPLMFIIQNTMVLDK 149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bka	NP_524867.2	PIN_Fcf1	58..192	CDD:189034	36/141 (26%)
UTP23	NP_115710.2	PIN_Fcf1-Utp23-H	2..148	CDD:189036	39/144 (27%)
UTP23	NP_115710.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1412
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810