Protein Alignment nec and Serpinb12

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_082247.1
• Gene: Serpinb12 / 71869
• MGIID: 1919119
• Length: 423
• Species: Mus musculus
• Alignment Length: 422
• Identity: 115/422 - (27%)
• Similarity: 186/422 - (44%)
• Gaps: 65/422 - (15%)

  Fly   108 DRFSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKA---GEFSKNAMAVAQD 169
            ::|..:.|:||.|..:.:|:...|.|:.|...::...:.|.:..::.:|   .|.||:......|
Mouse     9 NKFCFDFFREISKDDAHKNIFVCPLSLSAAFGMVRLGARGDSAHQIDEALHFNELSKDEHKEPND 73

  Fly   170 FESVIKYK---KHLEGADLTLAT----------------------------KVYY-----NRELG 198
            .....:.|   ..|||...|.|:                            |.||     ||..|
Mouse    74 PSPQSESKASDSSLEGQKQTSASQDQQGESTNDHQLLGCHFGKLLSRIDRDKSYYTLSMANRLYG 138

  Fly   199 ----GVNHSYDEYAKFYFSAGTEAVDMQ-NAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQA 258
                .:...|.:....:|....|:||.| :::.:..:||.||...::.||::|.....:|..|..
Mouse   139 EQEFPICSEYSDDVTEFFHTTVESVDFQKDSEKSRQEINFWVESQSQGKIKELFGKEAIDNSTVL 203

  Fly   259 LLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDS 323
            :|||||||:.:||.||.:.:|....|.........|.||.....:.:..:.||.|..||:.|...
Mouse   204 VLVNAVYFKAKWEREFNSENTVDASFCLNENEKKTVKMMNQKGKFRIGFIDELQAQILEMKYAMG 268

  Fly   324 ATSMLILLPNETTGLGKMLQQLSRPEFDLNRVAH----------RLRRQSVAVRLPKFQFEFEQD 378
            ..|||:|||:.:......||:|.:      ::.|          .|..:.||:..|:|..|...|
Mouse   269 KLSMLVLLPSCSEDNVNSLQELEK------KINHEKLLAWSSSENLSEKPVAISFPQFNLEDSYD 327

  Fly   379 MTEPLKNLGVHQMF-TPNSQVTKLMDQP-VRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPP 441
            :...|:::|:..:| ...:.:|.:...| :.:|||:.|.::.|.|.||:|:|||.......:| |
Mouse   328 LKSILQDMGIKDVFDETKADLTGISKSPNLYLSKIVHKTFVEVDEMGTQAAAASGVVAAEKAL-P 391

  Fly   442 KPTEFVANRPFVFAVR-TPA-SVLFIGHVEYP 471
            ...||.||.||:|.:| .|. |:||.|.|..|
Mouse   392 SWVEFNANHPFLFFIRHNPTQSLLFCGRVYCP 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	114/420 (27%)
Serpinb12	NP_082247.1	serpinB12_yukopin	1..423	CDD:381037	114/420 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..106		9/42 (21%)