Protein Alignment nec and Serpinb11

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_080143.1
• Gene: Serpinb11 / 66957
• MGIID: 1914207
• Length: 388
• Species: Mus musculus
• Alignment Length: 399
• Identity: 109/399 - (27%)
• Similarity: 201/399 - (50%)
• Gaps: 42/399 - (10%)

  Fly   102 PVFSYMDRFSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEF------- 159
            |:.:....|..::|||:..:...:|:.|||.:....|:::...:.||:..:::|...:
Mouse     3 PITTASTEFCLDVFKELSSNNVGENIFFSPLTTFYALSMLLLGTRGKSAEQMEKVLHYDSFSGVL 67

  Fly   160 ---SKNAMAVAQ------DFESVIKYKKHL-EGADLTLATKVYYNRELGGVNHSYDEYAKFYFSA 214
               :||:...:|      ||.::|   .|: :...|::|.::|..|.: ..:..|....:..:.|
Mouse    68 KAKTKNSSECSQVGVMHPDFRALI---SHINQQNSLSVANRIYGTRSI-SFHKQYVRCCEKLYQA 128

  Fly   215 GTEAVDMQ-NAKDTAAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMD 278
            ..:.||.: :.::|...|||||.:.|..||.:|.....:||.:..:||:|:||:|:|:::|...:
Mouse   129 KLQTVDFELSTEETRKSINAWVKNKTNGKITNLFAKGTIDPSSVMVLVSAIYFKGQWQNKFQKRE 193

  Fly   279 TSPYDFQHTNGRISKVAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLG---- 339
            |....|....|:.:.|.||:....:.||.:.|.....|||.|.::...|:||||..|..:.
Mouse   194 TVKAPFHMGVGKSAVVNMMYQTGTFKLAIIKEPEMQVLELPYANNKLRMIILLPVGTASVSQIEK 258

  Fly   340 ----KMLQQLSRPEFDLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMF-TPNSQVT 399
                |||::.:.|.   |.|     .:.|.|.:|||....:.|:...||:||:..:| ..|:.::
Mouse   259 HLNVKMLREWTNPS---NMV-----EREVDVHIPKFSLSVKYDLNTLLKSLGMRDIFNVANADLS 315

  Fly   400 KLM-DQPVRVSKILQKAYINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAV-RTPASV 462
            .:. |:.:.:||::.|:|::|.|.||||:||: .:.:.:...|...:|.||.||:|.: ....::
Mouse   316 GMSPDKGLYLSKVVHKSYVDVNEEGTEAAAAT-GESISVKRLPVTVQFTANCPFLFFIWDESGNI 379

  Fly   463 LFIGHVEYP 471
            ||.|....|
Mouse   380 LFAGKFASP 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	107/394 (27%)
Serpinb11	NP_080143.1	serpinB11_epipin	1..388	CDD:381036	108/397 (27%)
		RCL. /evidence=ECO:0000250	338..362		8/24 (33%)