Protein Alignment nec and Serpina3b

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_766612.1
• Gene: Serpina3b / 271047
• MGIID: 2182835
• Length: 420
• Species: Mus musculus
• Alignment Length: 365
• Identity: 92/365 - (25%)
• Similarity: 168/365 - (46%)
• Gaps: 36/365 - (9%)

  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSV-HALLALIYGASDGKTFRELQKAGEFSKNAMAVA---QDF 170
            |:...:||:......:|:.||||.: .||.:|..||. |.|..|:.:..:|:....:.|   |.|
Mouse    54 FAFSFYKELALKNPHKNIAFSPFGIATALNSLTLGAK-GNTLEEILEVLKFNLTETSEADIHQGF 117

  Fly   171 ESVIKYKKHLEGADLTLAT--KVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINA 233
            :.:::...| .|..:.:.|  .::..:.| .:...:.|.|:..:.......:.|...:....||:
Mouse   118 KHLLQRLSH-PGDQVQIRTGNALFVEKHL-QILAEFKEKARALYHTEVFTANFQQPHEAMKLINS 180

  Fly   234 WVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMM- 297
            ::.:.|:.||::||  :|:|..|..::||.::|:..|...|.:.||....|.....|..||.||
Mouse   181 YMSNQTQGKIKELV--SDMDGNTSMVIVNDLFFKAEWMVPFNSDDTFMGKFIVDRSRHVKVPMMK 243

  Fly   298 --------FNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQ-QLSRPEFDLN 353
                    |.|:        ||..|.:||.||.:..:|.| ||::    |||.| :.|.....|.
Mouse   244 TKNLRTPYFRDE--------ELKCTVVELNYKGNGKAMFI-LPDQ----GKMQQVEASLQPGTLK 295

  Fly   354 RVAHRLR-RQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD-QPVRVSKILQKAY 416
            :....|| |:...:.||||......::.:.|..||:.::|:..:.::.:.. :.:.||:::....
Mouse   296 KWRKSLRPRKIKELHLPKFSLSQHYNLEDILPELGIRELFSTQADLSGITGVKNITVSEMIHSTE 360

  Fly   417 INVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAV 456
            :::.|.|||..|.:...:..:|...||........|::.|
Mouse   361 LDMTEKGTEGDAITIVGYNFMSAKLKPVFVKFEDQFLYIV 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	92/365 (25%)
Serpina3b	NP_766612.1	serpinA3_A1AC	37..418	CDD:381019	92/365 (25%)
		RCL	367..392		7/24 (29%)